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dc.contributor.authorKasapcopur, Ozgur
dc.contributor.authorSozeri, Betul
dc.date.accessioned2021-03-02T23:12:44Z
dc.date.available2021-03-02T23:12:44Z
dc.date.issued2015
dc.identifier.citationSozeri B., Kasapcopur O., "Biological Agents in Familial Mediterranean Fever Focusing on Colchicine Resistance and Amyloidosis", CURRENT MEDICINAL CHEMISTRY, cilt.22, sa.16, ss.1986-1991, 2015
dc.identifier.issn0929-8673
dc.identifier.othervv_1032021
dc.identifier.otherav_111900bc-9dee-4e3a-93aa-183ab333c6aa
dc.identifier.urihttp://hdl.handle.net/20.500.12627/16987
dc.identifier.urihttps://doi.org/10.2174/0929867322666150311152300
dc.description.abstractFamilial Mediterranean fever (FMF) is the most common hereditary autoinflammatory syndrome. FMF is caused by mutations in the MEFV gene which encodes the pyrin protein. FMF is characterized by sporadic, paroxysmal attacks of fever and serosal inflammation, lasting 1-3 days. Patients may develop renal amyloidosis. Colchicine prevents attacks and renal amyloidosis. 5% to 10% of the patients with FMF are resistant or intolerant to colchicine. Colchicine resistant patients may receive biological therapies. Anti-interleukin-1 drugs are the most important agents of biological treatments. In this review, colchicine resistance and treatment options will be evaluated.
dc.language.isoeng
dc.subjectTemel Bilimler
dc.subjectSağlık Bilimleri
dc.subjectBİYOKİMYA VE MOLEKÜLER BİYOLOJİ
dc.subjectMoleküler Biyoloji ve Genetik
dc.subjectYaşam Bilimleri (LIFE)
dc.subjectKİMYA, TIP
dc.subjectKimya
dc.subjectTemel Bilimler (SCI)
dc.subjectFARMAKOLOJİ VE ECZACILIK
dc.subjectFarmakoloji ve Toksikoloji
dc.subjectEczacılık
dc.subjectTemel Eczacılık Bilimleri
dc.subjectYaşam Bilimleri
dc.subjectMoleküler Biyoloji ve Genetik
dc.subjectSitogenetik
dc.subjectBiyokimya
dc.titleBiological Agents in Familial Mediterranean Fever Focusing on Colchicine Resistance and Amyloidosis
dc.typeMakale
dc.relation.journalCURRENT MEDICINAL CHEMISTRY
dc.contributor.departmentEge Üniversitesi , ,
dc.identifier.volume22
dc.identifier.issue16
dc.identifier.startpage1986
dc.identifier.endpage1991
dc.contributor.firstauthorID42464


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