A longitudinal study of lateral ventricle volumes in deficit and non-deficit schizophrenia
Yazar
Eroglu, Seda
Erdogan, Yigit
KİTİŞ, ÖMER
GÖNÜL, ALİ SAFFET
HEPDURGUN, CENAN
Karakoc, Gulser
Polat, Irmak
Ozalay, Ozgun
Üst veri
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Although it is generally accepted that negative symptoms of schizophrenia are associated with larger lateral ventricles, this general assumption could not be validated in patients with primary negative symptoms. To elucidate this issue, we conducted a five-year longitudinal study, including deficit (n = 13) and non-deficit (n = 26) schizophrenia patients with healthy controls (n = 18). Analysis with linear mixed effects modeling showed that both the left and the right lateral ventricles of the deficit patients enlarged more than the non-deficit patients. Our results suggest that structural alterations in deficit patients might follow a different trajectory than those in non-deficit patients.
Bağlantı
http://hdl.handle.net/20.500.12627/170021https://doi.org/10.1016/j.pscychresns.2021.111311
Koleksiyonlar
- Makale [92796]