dc.contributor.author | Tuna Deveci, Rumeysa | |
dc.contributor.author | Demirkol, Demet | |
dc.contributor.author | Derviş, Melda F | |
dc.contributor.author | Sencer, Serra | |
dc.contributor.author | Peker, Bariş | |
dc.contributor.author | Ağrali Eröz, Nesli | |
dc.date.accessioned | 2021-12-10T10:31:42Z | |
dc.date.available | 2021-12-10T10:31:42Z | |
dc.identifier.citation | Ağrali Eröz N., Derviş M. F. , Tuna Deveci R., Sencer S., Peker B., Demirkol D., "Intracranial Hemorrhage Associated With T-Cell Acute Lymphoblastic Leukemia With Hyperleukocytosis: A Case Report.", Journal of pediatric hematology/oncology, cilt.43, 2021 | |
dc.identifier.issn | 1077-4114 | |
dc.identifier.other | vv_1032021 | |
dc.identifier.other | av_45684b9f-60fc-47a0-9d2f-668951be239c | |
dc.identifier.uri | http://hdl.handle.net/20.500.12627/170068 | |
dc.identifier.uri | https://doi.org/10.1097/mph.0000000000002027 | |
dc.description.abstract | Acute leukemia in children may present with hyperleukocytosis. Symptomatic hyperleukocytosis is a medical emergency that necessitates rapid stabilization of the patient and prompt lowering of the leukocyte count. We report on a patient with intracranial hemorrhage associated with T-cell acute lymphoblastic leukemia with hyperleukocytosis, which is a rare occurrence. A 16-year-old boy with hyperleukocytosis (total white cell count; 398x10(3)/mu L) underwent repeated leukapheresis and received supportive treatment until a definite diagnosis of T-cell acute lymphoblastic leukemia was made and chemotherapy was started at 10% of the usual dose. On day 2 of treatment, he had headache, vomiting, and was agitated. Brain magnetic resonance imaging showed bilateral extensive hemispheric and cerebellar punctate areas of hemorrhage and perilesional edema. Chemotherapy intensified to a maximum dose on day 3. If supportive care for tumor lysis syndrome can be promptly provided, initial chemotherapy regimen can immediately be begun at an optimal dose. | |
dc.language.iso | eng | |
dc.subject | Klinik Tıp (MED) | |
dc.subject | PEDİATRİ | |
dc.subject | HEMATOLOJİ | |
dc.subject | Klinik Tıp | |
dc.subject | ONKOLOJİ | |
dc.title | Intracranial Hemorrhage Associated With T-Cell Acute Lymphoblastic Leukemia With Hyperleukocytosis: A Case Report. | |
dc.type | Makale | |
dc.relation.journal | Journal of pediatric hematology/oncology | |
dc.contributor.department | , , | |
dc.identifier.volume | 43 | |
dc.contributor.firstauthorID | 2684845 | |