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dc.contributor.authorKarahan, Gonca Emel
dc.contributor.authorKekik, Cigdem
dc.contributor.authorPinarbasi, Binnur
dc.contributor.authorSeyhun, Yalcin
dc.contributor.authorKaymakoglu, Sabahattin
dc.contributor.authorDemir, Kadir
dc.contributor.authorCarin, Mahmut
dc.date.accessioned2021-03-02T23:14:15Z
dc.date.available2021-03-02T23:14:15Z
dc.date.issued2010
dc.identifier.citationKekik C., Seyhun Y., Karahan G. E. , Pinarbasi B., Demir K., Kaymakoglu S., Carin M., "Association of HLA-DRB1 Alleles and Autoimmune Hepatitis in Turkish Patients", TRAKYA UNIVERSITESI TIP FAKULTESI DERGISI, cilt.27, sa.3, ss.253-256, 2010
dc.identifier.issn1301-3149
dc.identifier.otherav_1141723c-5f75-4134-8799-13bf2eea1cf1
dc.identifier.othervv_1032021
dc.identifier.urihttp://hdl.handle.net/20.500.12627/17102
dc.identifier.urihttps://doi.org/10.5174/tutfd.2009.02045.1
dc.description.abstractObjectives: Autoimmune hepatitis (AIH) which is characterized by hypergammaglobulinemia and a wide range of circulating auto antibodies is a necro-inflammatory liver disease of unknown aetiology. Immunogenetic studies have shown the association of autoimmunity with HLA (Human Leukocyte Antigen) alleles. Furthermore, they have shown a decrease in the expression of HLA antigens on lymphocyte surface and a dysregulation of gene expression arranged by HLA. A significant association is found between AIH and HLA-DRB1(star)03, (star)04 and (star)13 alleles in various studies. We performed HLA-DRB1 genotyping in Turkish patients with AIH.
dc.language.isoeng
dc.subjectKlinik Tıp (MED)
dc.subjectSağlık Bilimleri
dc.subjectTIP, GENEL & İÇECEK
dc.subjectKlinik Tıp
dc.subjectTıp
dc.subjectTemel Tıp Bilimleri
dc.titleAssociation of HLA-DRB1 Alleles and Autoimmune Hepatitis in Turkish Patients
dc.typeMakale
dc.relation.journalTRAKYA UNIVERSITESI TIP FAKULTESI DERGISI
dc.contributor.departmentİstanbul Üniversitesi , ,
dc.identifier.volume27
dc.identifier.issue3
dc.identifier.startpage253
dc.identifier.endpage256
dc.contributor.firstauthorID69867


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