dc.contributor.author | Karahan, Gonca Emel | |
dc.contributor.author | Kekik, Cigdem | |
dc.contributor.author | Pinarbasi, Binnur | |
dc.contributor.author | Seyhun, Yalcin | |
dc.contributor.author | Kaymakoglu, Sabahattin | |
dc.contributor.author | Demir, Kadir | |
dc.contributor.author | Carin, Mahmut | |
dc.date.accessioned | 2021-03-02T23:14:15Z | |
dc.date.available | 2021-03-02T23:14:15Z | |
dc.date.issued | 2010 | |
dc.identifier.citation | Kekik C., Seyhun Y., Karahan G. E. , Pinarbasi B., Demir K., Kaymakoglu S., Carin M., "Association of HLA-DRB1 Alleles and Autoimmune Hepatitis in Turkish Patients", TRAKYA UNIVERSITESI TIP FAKULTESI DERGISI, cilt.27, sa.3, ss.253-256, 2010 | |
dc.identifier.issn | 1301-3149 | |
dc.identifier.other | av_1141723c-5f75-4134-8799-13bf2eea1cf1 | |
dc.identifier.other | vv_1032021 | |
dc.identifier.uri | http://hdl.handle.net/20.500.12627/17102 | |
dc.identifier.uri | https://doi.org/10.5174/tutfd.2009.02045.1 | |
dc.description.abstract | Objectives: Autoimmune hepatitis (AIH) which is characterized by hypergammaglobulinemia and a wide range of circulating auto antibodies is a necro-inflammatory liver disease of unknown aetiology. Immunogenetic studies have shown the association of autoimmunity with HLA (Human Leukocyte Antigen) alleles. Furthermore, they have shown a decrease in the expression of HLA antigens on lymphocyte surface and a dysregulation of gene expression arranged by HLA. A significant association is found between AIH and HLA-DRB1(star)03, (star)04 and (star)13 alleles in various studies. We performed HLA-DRB1 genotyping in Turkish patients with AIH. | |
dc.language.iso | eng | |
dc.subject | Klinik Tıp (MED) | |
dc.subject | Sağlık Bilimleri | |
dc.subject | TIP, GENEL & İÇECEK | |
dc.subject | Klinik Tıp | |
dc.subject | Tıp | |
dc.subject | Temel Tıp Bilimleri | |
dc.title | Association of HLA-DRB1 Alleles and Autoimmune Hepatitis in Turkish Patients | |
dc.type | Makale | |
dc.relation.journal | TRAKYA UNIVERSITESI TIP FAKULTESI DERGISI | |
dc.contributor.department | İstanbul Üniversitesi , , | |
dc.identifier.volume | 27 | |
dc.identifier.issue | 3 | |
dc.identifier.startpage | 253 | |
dc.identifier.endpage | 256 | |
dc.contributor.firstauthorID | 69867 | |