| dc.contributor.author | Shetty, J. K. | |
| dc.contributor.author | Kattamis, A. | |
| dc.contributor.author | Vlachaki, E. | |
| dc.contributor.author | Origa, R. | |
| dc.contributor.author | Aydinok, Y. | |
| dc.contributor.author | Bejaoui, M. | |
| dc.contributor.author | Ho, P. J. | |
| dc.contributor.author | Chew, L. -P. | |
| dc.contributor.author | Bee, P. -C. | |
| dc.contributor.author | Lim, S. -M. | |
| dc.contributor.author | Lu, M. -Y. | |
| dc.contributor.author | Tantiworawit, A. | |
| dc.contributor.author | Ganeva, P. | |
| dc.contributor.author | Gercheva, L. | |
| dc.contributor.author | Shah, F. | |
| dc.contributor.author | Neufeld, E. J. | |
| dc.contributor.author | Thompson, A. | |
| dc.contributor.author | Laadem, A. | |
| dc.contributor.author | Lal, A. | |
| dc.contributor.author | Zou, J. | |
| dc.contributor.author | Zhang, J. | |
| dc.contributor.author | Miteva, D. | |
| dc.contributor.author | Zinger, T. | |
| dc.contributor.author | Linde, P. G. | |
| dc.contributor.author | Sherman, M. L. | |
| dc.contributor.author | Hermine, O. | |
| dc.contributor.author | Porter, J. | |
| dc.contributor.author | Piga, A. | |
| dc.contributor.author | Cappellini, M. D. | |
| dc.contributor.author | Viprakasit, V. | |
| dc.contributor.author | Taher, A. T. | |
| dc.contributor.author | Georgiev, P. | |
| dc.contributor.author | Kuo, K. H. M. | |
| dc.contributor.author | Coates, T. | |
| dc.contributor.author | Voskaridou, E. | |
| dc.contributor.author | Liew, H. -K. | |
| dc.contributor.author | Pazgal-Kobrowski, I. | |
| dc.contributor.author | Forni, G. L. | |
| dc.contributor.author | Perrotta, S. | |
| dc.contributor.author | Khelif, A. | |
| dc.date.accessioned | 2021-12-10T12:39:49Z | |
| dc.date.available | 2021-12-10T12:39:49Z | |
| dc.date.issued | 2020 | |
| dc.identifier.citation | Cappellini M. D. , Viprakasit V., Taher A. T. , Georgiev P., Kuo K. H. M. , Coates T., Voskaridou E., Liew H. -. , Pazgal-Kobrowski I., Forni G. L. , et al., "A Phase 3 Trial of Luspatercept in Patients with Transfusion-Dependent beta-Thalassemia", NEW ENGLAND JOURNAL OF MEDICINE, cilt.382, sa.13, ss.1219-1231, 2020 | |
| dc.identifier.issn | 0028-4793 | |
| dc.identifier.other | av_cd6fcb57-872c-4a0d-b811-2c7ce51a11c5 | |
| dc.identifier.other | vv_1032021 | |
| dc.identifier.uri | http://hdl.handle.net/20.500.12627/174364 | |
| dc.identifier.uri | https://doi.org/10.1056/nejmoa1910182 | |
| dc.description.abstract | Background Patients with transfusion-dependent beta-thalassemia need regular red-cell transfusions. Luspatercept, a recombinant fusion protein that binds to select transforming growth factor beta superfamily ligands, may enhance erythroid maturation and reduce the transfusion burden (the total number of red-cell units transfused) in such patients. | |
| dc.language.iso | eng | |
| dc.subject | General Health Professions | |
| dc.subject | Pathophysiology | |
| dc.subject | Internal Medicine | |
| dc.subject | Assessment and Diagnosis | |
| dc.subject | Medicine (miscellaneous) | |
| dc.subject | General Medicine | |
| dc.subject | Health Sciences | |
| dc.subject | Fundamentals and Skills | |
| dc.subject | Tıp | |
| dc.subject | Sağlık Bilimleri | |
| dc.subject | Family Practice | |
| dc.subject | Temel Tıp Bilimleri | |
| dc.subject | TIP, GENEL & İÇECEK | |
| dc.subject | Klinik Tıp | |
| dc.subject | Klinik Tıp (MED) | |
| dc.title | A Phase 3 Trial of Luspatercept in Patients with Transfusion-Dependent beta-Thalassemia | |
| dc.type | Makale | |
| dc.relation.journal | NEW ENGLAND JOURNAL OF MEDICINE | |
| dc.contributor.department | University Of Milan , , | |
| dc.identifier.volume | 382 | |
| dc.identifier.issue | 13 | |
| dc.identifier.startpage | 1219 | |
| dc.identifier.endpage | 1231 | |
| dc.contributor.firstauthorID | 2741837 | |