| dc.contributor.author | Topuz, Sibel | |
| dc.contributor.author | ÖZHAN, Gül | |
| dc.contributor.author | ALPERTUNGA, Büket | |
| dc.date.accessioned | 2021-12-10T12:42:56Z | |
| dc.date.available | 2021-12-10T12:42:56Z | |
| dc.date.issued | 2003 | |
| dc.identifier.citation | ÖZHAN G., Topuz S., ALPERTUNGA B., "Determination of cyclonite (RDX) in human plasma by high-performance liquid chromatography", Farmaco, cilt.58, sa.6, ss.445-448, 2003 | |
| dc.identifier.issn | 0014-827X | |
| dc.identifier.other | vv_1032021 | |
| dc.identifier.other | av_d1677236-54c3-4cda-8860-bc636cf41e83 | |
| dc.identifier.uri | http://hdl.handle.net/20.500.12627/174487 | |
| dc.identifier.uri | https://doi.org/10.1016/s0014-827x(03)00069-7 | |
| dc.identifier.uri | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=0038289240&origin=inward | |
| dc.description.abstract | A simple and sensitive HPLC method has been developed for the assay of cyclonite (RDX) in human plasma. The assay involves solid-phase extraction on Tox-clean RC SPE cartridges and isocratic reversed-phase chromatography with diode-array detection. The assay was linear over the concentration range of 0.01-2.0 μg/ml for plasma with a lower limit of detection of 0.005 μg/ml. Both the within-day and day-to-day reproducibilities and accuracies were less than 10.15 and 1.9%, respectively. The method was applied to evaluate RDX concentration in plasma samples obtained from soldiers exposed RDX. © 2003 Éditions scientifiques et médicales Elsevier SAS. All rights reserved. | |
| dc.language.iso | eng | |
| dc.subject | Temel Bilimler | |
| dc.subject | Pharmaceutical Science | |
| dc.subject | Life Sciences | |
| dc.subject | Drug Discovery | |
| dc.subject | Klinik Tıp | |
| dc.subject | Moleküler Biyoloji ve Genetik | |
| dc.subject | TROPİKAL TIP | |
| dc.subject | BİYOKİMYA VE MOLEKÜLER BİYOLOJİ | |
| dc.subject | Tıp | |
| dc.subject | Sağlık Bilimleri | |
| dc.subject | Yaşam Bilimleri | |
| dc.subject | Moleküler Biyoloji ve Genetik | |
| dc.subject | Sitogenetik | |
| dc.subject | Klinik Tıp (MED) | |
| dc.subject | Yaşam Bilimleri (LIFE) | |
| dc.title | Determination of cyclonite (RDX) in human plasma by high-performance liquid chromatography | |
| dc.type | Makale | |
| dc.relation.journal | Farmaco | |
| dc.contributor.department | İstanbul Üniversitesi , Eczacılık Fakültesi , Eczacılık Meslek Bilimleri Bölümü | |
| dc.identifier.volume | 58 | |
| dc.identifier.issue | 6 | |
| dc.identifier.startpage | 445 | |
| dc.identifier.endpage | 448 | |
| dc.contributor.firstauthorID | 2639384 | |
