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Recent Advances on Topical Application of Ceramides to Restore Barrier Function of Skin

dc.contributor.authorGÜNGÖR, Sevgi
dc.contributor.authorBektay, Humeyra Sahin
dc.contributor.authorKaykin, Melis
dc.contributor.authorKahraman, Emine
dc.date.accessioned2021-12-10T12:57:09Z
dc.date.available2021-12-10T12:57:09Z
dc.date.issued2019
dc.identifier.citationKahraman E., Kaykin M., Bektay H. S. , GÜNGÖR S., "Recent Advances on Topical Application of Ceramides to Restore Barrier Function of Skin", COSMETICS, cilt.6, sa.3, 2019
dc.identifier.othervv_1032021
dc.identifier.otherav_e4953bf5-02ac-4d93-beef-a5c5fd579972
dc.identifier.urihttp://hdl.handle.net/20.500.12627/175081
dc.identifier.urihttps://doi.org/10.3390/cosmetics6030052
dc.identifier.urihttps://avesis.istanbul.edu.tr/api/publication/e4953bf5-02ac-4d93-beef-a5c5fd579972/file
dc.description.abstractHuman skin is the largest organ of the body and is an effective physical barrier keeping it from environmental conditions. This barrier function of the skin is based on stratum corneum, located in the uppermost skin. Stratum corneum has corneocytes surrounded by multilamellar lipid membranes which are composed of cholesterol, free fatty acids and ceramides (CERs). Alterations in ceramide content of the stratum corneum are associated with numerous skin disorders. In recent years, CERs have been incorporated into conventional and novel carrier systems with the purpose of exogenously applying CERs to help the barrier function of the skin. This review provides an overview of the structure, function and importance of CERs to restore the barrier function of the skin following their topical application.
dc.language.isoeng
dc.subjectMoleküler Biyoloji ve Genetik
dc.subjectSitogenetik
dc.subjectTemel Bilimler
dc.subjectBiochemistry, Genetics and Molecular Biology (miscellaneous)
dc.subjectClinical Biochemistry
dc.subjectCancer Research
dc.subjectMolecular Biology
dc.subjectDrug Discovery
dc.subjectAging
dc.subjectGeneral Biochemistry, Genetics and Molecular Biology
dc.subjectStructural Biology
dc.subjectDermatology
dc.subjectLife Sciences
dc.subjectHealth Sciences
dc.subjectBiochemistry
dc.subjectBİYOKİMYA VE MOLEKÜLER BİYOLOJİ
dc.subjectMoleküler Biyoloji ve Genetik
dc.subjectYaşam Bilimleri (LIFE)
dc.subjectDERMATOLOJİ
dc.subjectKlinik Tıp
dc.subjectKlinik Tıp (MED)
dc.subjectTıp
dc.subjectSağlık Bilimleri
dc.subjectDahili Tıp Bilimleri
dc.subjectDermatoloji
dc.subjectYaşam Bilimleri
dc.titleRecent Advances on Topical Application of Ceramides to Restore Barrier Function of Skin
dc.typeMakale
dc.relation.journalCOSMETICS
dc.contributor.departmentİstanbul Üniversitesi , ,
dc.identifier.volume6
dc.identifier.issue3
dc.contributor.firstauthorID2741064


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