dc.contributor.author | Dogusoy, Gulen | |
dc.contributor.author | Onal, Zerrin | |
dc.contributor.author | Dogan, Yasar | |
dc.contributor.author | Kutlu, Tufan | |
dc.contributor.author | Erkan, Tulay | |
dc.contributor.author | Usta, Merve | |
dc.contributor.author | Cokugras, Fugen Cullu | |
dc.date.accessioned | 2021-03-02T23:23:17Z | |
dc.date.available | 2021-03-02T23:23:17Z | |
dc.identifier.citation | Dogan Y., Erkan T., Onal Z., Usta M., Dogusoy G., Cokugras F. C. , Kutlu T., "Lactoferrin Levels in the Gastric Tissue of Helicobacter pylori-Positive and -Negative Patients and Its Effect on Anemia", MEDIATORS OF INFLAMMATION, cilt.2012, 2012 | |
dc.identifier.issn | 0962-9351 | |
dc.identifier.other | vv_1032021 | |
dc.identifier.other | av_12274e09-3d74-4ae3-9c28-cba024a94591 | |
dc.identifier.uri | http://hdl.handle.net/20.500.12627/17669 | |
dc.identifier.uri | https://doi.org/10.1155/2012/214581 | |
dc.description.abstract | Aim. To determine gastric tissue lactoferrin (Lf) levels of Helicobacter pylori- (Hp-) positive and -negative patients and its effect on anemia. Methods. Cases in which initial presentation was of abdominal pain and that were Hp-positive at endoscopy were included. Hp-positive cases and -negative controls were divided into two groups. Results. The study included 64 cases (average: 10.2 +/- 0.4 years, 39 male and 25 female). Lf levels were subsequently studied on 61 cases. 45 (73.8%) of these were Hp-positive, while 16 (22.2%) were Hp-negative. In Hp-positive cases, mean staining percentages and density of glands in the antral mucosa were 45.5 +/- 4.7% and 1.9 +/- 0.1, respectively. Hp-negative cases showed significantly different values of 17.8 +/- 4.5% and 1.3 +/- 0.2, respectively. Hemoglobin and serum ferritin values of Hp-positive cases were 12.7 +/- 0.2 g/dL and 32.5 +/- 2ng/mL, but these were comparable with Hp-negative cases (12.6 +/- 0.1 g/dL and 30.7 +/- 4.4ng/mL). Conclusions. Tissue Lf was significantly higher in Hp-positive cases compared to Hp-negative cases, but no difference was observed between the two groups with regards to hemoglobin and ferritin level. As a result, it is difficult to say that this rise in Lf plays a role in the development of iron deficiency anemia in Hp-positive patients. | |
dc.language.iso | eng | |
dc.subject | Histoloji-Embriyoloji | |
dc.subject | Yaşam Bilimleri | |
dc.subject | Moleküler Biyoloji ve Genetik | |
dc.subject | Temel Bilimler | |
dc.subject | Sağlık Bilimleri | |
dc.subject | Temel Tıp Bilimleri | |
dc.subject | Tıp | |
dc.subject | İmmünoloji | |
dc.subject | Yaşam Bilimleri (LIFE) | |
dc.subject | Moleküler Biyoloji ve Genetik | |
dc.subject | HÜCRE BİYOLOJİSİ | |
dc.title | Lactoferrin Levels in the Gastric Tissue of Helicobacter pylori-Positive and -Negative Patients and Its Effect on Anemia | |
dc.type | Makale | |
dc.relation.journal | MEDIATORS OF INFLAMMATION | |
dc.contributor.department | İstanbul Üniversitesi , , | |
dc.identifier.volume | 2012 | |
dc.contributor.firstauthorID | 30774 | |