Lupus Vulgaris Secondary to BCG Vaccination Without Indication

Abstract

Lupus vulgaris, a common form of the skin tuberculosis is rarely developed following BCG (Bacille Calmette- Guerin) vaccination in the area of injection. In this paper, a 38 year-old healthy woman which developed lupus vulgaris 3 weeks after intradermal BCG vaccination is reported. The lesion appeared following BCG vaccination by a tuberculosis-screening health group without any indication after applying a tuberculin (PPD) test. The clinical and histopathological investigations were characteristic for lupus vulgaris. Acid-fast stains and cultures prepared from the tissue were negative. As 6 month period of two-drug antituberculous therapy led to relative regression, the treatment was completed by three sessions of cryosurgery.