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dc.contributor.authorAksu, Ugur
dc.contributor.authorDEMİRCİ TANSEL, Cihan
dc.contributor.authorBelce, Ahmet
dc.date.accessioned2022-02-18T09:37:56Z
dc.date.available2022-02-18T09:37:56Z
dc.date.issued2013
dc.identifier.citationAksu U., Belce A., DEMİRCİ TANSEL C., "The Role of Beta-3-Adrenoceptors in Autonomic Nervous System", BEZMIALEM SCIENCE, cilt.1, sa.1, ss.16-20, 2013
dc.identifier.otherav_4e78c3ee-bba4-45b5-b3fb-50bff0843424
dc.identifier.othervv_1032021
dc.identifier.urihttp://hdl.handle.net/20.500.12627/177613
dc.identifier.urihttps://doi.org/10.5152/bs.2013.1387
dc.description.abstractCatecholamines play a regulatory role in the cardiovascular system, primarily via beta (1-2)-adrenoreceptors (AR). However, in the late 1980s, the cloning of a third beta-AR subtype (beta 3-AR) in the heart has altered the conventional view on the regulation of heart function via the betaadrenergic receptors. Additionally, in blood vessels, beta 3-AR was shown to produce relaxation. Currently, the physiological role of beta 3-AR is not clearly known. Hence, the purpose of this review is to summarize the physiological evidences supporting the functional roles of beta 3-AR in various tissues, particularly cardiac and vascular. In addition, this review discusses the potential role of beta 3-AR in obesity and insulin resistance and emphasizes their putative involvement as new therapeutic targets.
dc.language.isoeng
dc.subjectGeneral Health Professions
dc.subjectPathophysiology
dc.subjectInternal Medicine
dc.subjectAssessment and Diagnosis
dc.subjectMedicine (miscellaneous)
dc.subjectGeneral Medicine
dc.subjectHealth Sciences
dc.subjectTIP, GENEL & İÇECEK
dc.subjectTemel Tıp Bilimleri
dc.subjectFamily Practice
dc.subjectFundamentals and Skills
dc.subjectSağlık Bilimleri
dc.subjectTıp
dc.subjectKlinik Tıp (MED)
dc.subjectKlinik Tıp
dc.titleThe Role of Beta-3-Adrenoceptors in Autonomic Nervous System
dc.typeMakale
dc.relation.journalBEZMIALEM SCIENCE
dc.contributor.departmentİstanbul Teknik Üniversitesi , ,
dc.identifier.volume1
dc.identifier.issue1
dc.identifier.startpage16
dc.identifier.endpage20
dc.contributor.firstauthorID3381452


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