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dc.contributor.authorYarman, S
dc.contributor.authorAZIZLERLI, Halil Dinçer
dc.contributor.authorAdemoglu, Evin
dc.contributor.authorGokkusu, CAHİDE
dc.date.accessioned2021-03-02T23:26:25Z
dc.date.available2021-03-02T23:26:25Z
dc.date.issued1998
dc.identifier.citationAdemoglu E., Gokkusu C., Yarman S., AZIZLERLI H. D. , "The effect of methimazole on the oxidant and antioxidant system in patients with hyperthyroidism", PHARMACOLOGICAL RESEARCH, cilt.38, sa.2, ss.93-96, 1998
dc.identifier.issn1043-6618
dc.identifier.othervv_1032021
dc.identifier.otherav_12776f0d-7239-4c43-8a40-3c508d1bb918
dc.identifier.urihttp://hdl.handle.net/20.500.12627/17856
dc.identifier.urihttps://doi.org/10.1006/phrs.1998.0336
dc.description.abstractThe present study was designed to evaluate the changes in the plasma lipid peroxidation and antioxidant system in 15 adult volunteer patients in hyperthyroid and euthyroid states. In these patients, plasma concentrations of lipid peroxides were decreased and, ascorbic acid and vitamin E levels were significantly increased in euthyroid status in comparison to hyperthyroid status. A significant increase in the plasma GPx activity (P < 0.01) and a decrease in GST (P < 0.001) was observed after euthyroidism was sustained with methimazole therapy. In conclusion, hyperthyroidism tends to enhance lipid peroxide content and an increase in GST and decreases in GPx, vitamin E and ascorbic acid levels accompany to this change in the plasma. The achievement of euthyroidism led an improvement in these parameters. (C) 1998 The Italian Pharmacological Society.
dc.language.isoeng
dc.subjectFarmakoloji ve Toksikoloji
dc.subjectYaşam Bilimleri (LIFE)
dc.subjectSağlık Bilimleri
dc.subjectEczacılık
dc.subjectTemel Eczacılık Bilimleri
dc.subjectYaşam Bilimleri
dc.subjectTemel Bilimler
dc.subjectFARMAKOLOJİ VE ECZACILIK
dc.titleThe effect of methimazole on the oxidant and antioxidant system in patients with hyperthyroidism
dc.typeMakale
dc.relation.journalPHARMACOLOGICAL RESEARCH
dc.contributor.department, ,
dc.identifier.volume38
dc.identifier.issue2
dc.identifier.startpage93
dc.identifier.endpage96
dc.contributor.firstauthorID54695


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