Paracetamol and propyphenazone hypersensitivity among intolerance reactions to analgesic drugs

Abstract

Objective: Hypersensitivity reactions (HR) to paracetamol are reported less commonly compared to other nonsteroidal antiinflammatory (NSAI) drugs. The aim of this study was to determine the rate of HR to paracetamol and paracetamol-propyphenazone combination (P-P) drugs in patients with analgesic intolerance and to assess the possible relations between HR to these drugs and other NSAI drugs as well as atopic diseases.