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dc.contributor.authorSag, Elif
dc.contributor.authorÇAKIR, MURAT
dc.contributor.authorORHAN, FAZIL
dc.contributor.authorSAYGIN, İSMAİL
dc.date.accessioned2022-02-18T10:57:29Z
dc.date.available2022-02-18T10:57:29Z
dc.date.issued2020
dc.identifier.citationÇAKIR M., Sag E., SAYGIN İ., ORHAN F., "Ileocolonic Lymphonodular Hyperplasia in Children Related to Etiologies Ranging from Food Hypersensitivity to Familial Mediterranean Fever", MEDICAL PRINCIPLES AND PRACTICE, cilt.29, sa.5, ss.473-479, 2020
dc.identifier.issn1011-7571
dc.identifier.otherav_caa3e8d1-ed0c-4699-b608-22bc8db5895d
dc.identifier.othervv_1032021
dc.identifier.urihttp://hdl.handle.net/20.500.12627/180231
dc.identifier.urihttps://doi.org/10.1159/000506257
dc.identifier.urihttps://avesis.istanbul.edu.tr/api/publication/caa3e8d1-ed0c-4699-b608-22bc8db5895d/file
dc.description.abstractObjective:We aimed to share our observations on the demographics, clinical characteristics, and outcomes of lymphonodular hyperplasia (LNH) in children.Subjects and Methods:The study included children on whom colonoscopy was performed between January 2015 and May 2018 (n= 361). Demographics, treatment modalities, and outcomes of the patients with LNH were recorded.Results:LNH was found in 66 patients (18.3%; mean age 8.6 +/- 5.96 years, 59.1% male). We found that the etiologic factors were food hypersensitivity (FH) in 25 (37.8%), nonspecific colitis in 12 (18.2%), irritable bowel syndrome in 10 (15.2%), familial Mediter-ranean fever in 7 (10.6%), primary immunodeficiency in 4 (6.1%), and intestinal dysmotility, oxyuriasis, Crohn's disease, and giardiasis in 1 (1.5%) patient. Additionally, in the genetic analysis of patients with idiopathic LNH (n= 4), we detected heterozygoteMEFVmutations in all. Cow's milk and egg (25%) were the most common allergens in patients with FH. Symptoms of all patients (n= 25) improved after an elimination diet.Conclusions:LNH is a common finding in pediatric colonoscopies with a variety of etiologies ranging from FH and familial Mediterranean fever to immunodeficiency.
dc.language.isoeng
dc.subjectHealth Sciences
dc.subjectTemel Tıp Bilimleri
dc.subjectFamily Practice
dc.subjectFundamentals and Skills
dc.subjectGeneral Health Professions
dc.subjectPathophysiology
dc.subjectInternal Medicine
dc.subjectAssessment and Diagnosis
dc.subjectMedicine (miscellaneous)
dc.subjectGeneral Medicine
dc.subjectTIP, GENEL & İÇECEK
dc.subjectKlinik Tıp
dc.subjectKlinik Tıp (MED)
dc.subjectTıp
dc.subjectSağlık Bilimleri
dc.titleIleocolonic Lymphonodular Hyperplasia in Children Related to Etiologies Ranging from Food Hypersensitivity to Familial Mediterranean Fever
dc.typeMakale
dc.relation.journalMEDICAL PRINCIPLES AND PRACTICE
dc.contributor.departmentKaradeniz Teknik Üniversitesi , Tıp Fakültesi , Dahili Tıp
dc.identifier.volume29
dc.identifier.issue5
dc.identifier.startpage473
dc.identifier.endpage479
dc.contributor.firstauthorID3061040


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