A Case of Ciprofloxacin Induced Delirium

Abstract

A previously healthy 82-year-old woman presented with acute-onset delirium with psychotic features as a consequence of ciprofloxacin therapy. Withdrawal of the medication was associated with return of the patient's normal mental status. The quinolones called gyrase inhibitors are known for their potential to cause central nervous system-related adverse effects, including headache and insomnia. Risk factors for neurotoxicity include renal insufficiency, underlying central nervous system (CNS) disease and increased CNS penetration of drug. Acute delirium resulting from ciprofloxacin therapy is an exceedingly rare complication that has been thought to occur more commonly in elderly patients. Herein, we described that a ciprofloxacin induced delirium case after ciprofloxacin use.