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dc.contributor.authorAbdassalam, Aesha Fsh
dc.contributor.authorDENİZ, NAHİDE GÜLŞAH
dc.contributor.authorSAYIL, MAKBULE ÇİĞDEM
dc.contributor.authorÖZYÜREK, MUSTAFA
dc.contributor.authorYesil, Emin Ahmet
dc.contributor.authorSalihoglu, Huseyin
dc.date.accessioned2022-07-04T12:53:14Z
dc.date.available2022-07-04T12:53:14Z
dc.date.issued2022
dc.identifier.citationAbdassalam A. F. , DENİZ N. G. , SAYIL M. Ç. , ÖZYÜREK M., Yesil E. A. , Salihoglu H., "Synthesis of New Regioisomers of 5-Nitro-1,4-Naphthoquinone, Evaluation of Antioxidant and Catalase Inhibition Activities", ACTA CHIMICA SLOVENICA, cilt.69, sa.1, ss.187-199, 2022
dc.identifier.issn1318-0207
dc.identifier.otherav_30847455-7e6f-4a94-9c16-f90b9fa18c66
dc.identifier.othervv_1032021
dc.identifier.urihttp://hdl.handle.net/20.500.12627/182174
dc.identifier.urihttps://doi.org/10.17344/acsi.2021.7123
dc.description.abstractThe studies on nitronaphthoquinone derivatives are rare in the literature, and the nitro group associated with the aromatic ring in the quinone system is known to increase the biological activity of naphthoquinone due to its electron-withdrawing properties. In the course of quinone derivatives, the new N(H)-substituted-5-nitro-1,4-naphthoquinones (NQ) as regioisomers were synthesized by reactions of 2,3-dichloro-5-nitro-1,4-naphthoquinone with some heterocyclic ring substituted nucleophiles such as anilines, piperazines, or morpholines, according to a Michael 1,4-addition mechanism. Five NQ regioisomer couples having different functional group (2-chloro-isomers 3, 5, 7, 9 and 13; 3-chloro-isomers 2, 4, 6, 8 and 12) are reported here. All new synthesized compounds were characterized by spectroscopic methods and two-dimensional NMR techniques H-1-H-1 correlated spectroscopy (COSY).
dc.language.isoeng
dc.subjectChemistry (miscellaneous)
dc.subjectKİMYA, MULTİDİSİPLİNER
dc.subjectKimya
dc.subjectTemel Bilimler (SCI)
dc.subjectBiyokimya
dc.subjectGeneral Chemistry
dc.subjectPhysical Sciences
dc.subjectAlkoloidler
dc.subjectTemel Bilimler
dc.titleSynthesis of New Regioisomers of 5-Nitro-1,4-Naphthoquinone, Evaluation of Antioxidant and Catalase Inhibition Activities
dc.typeMakale
dc.relation.journalACTA CHIMICA SLOVENICA
dc.contributor.departmentİstanbul Üniversitesi-Cerrahpaşa , ,
dc.identifier.volume69
dc.identifier.issue1
dc.identifier.startpage187
dc.identifier.endpage199
dc.contributor.firstauthorID3407071


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