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dc.contributor.authorİNSEL, Mert Akın
dc.contributor.authorÜSTÜN ALKAN, FULYA
dc.contributor.authorKahyaoglu, Ibrahim Mizan
dc.contributor.authorALBAYRAK, Fatma İnci
dc.contributor.authorKARAKUŞ, SELCAN
dc.date.accessioned2022-07-04T12:57:00Z
dc.date.available2022-07-04T12:57:00Z
dc.identifier.citationKARAKUŞ S., İNSEL M. A. , Kahyaoglu I. M. , ALBAYRAK F. İ. , ÜSTÜN ALKAN F., "Characterization, optimization, and evaluation of preservative efficacy of carboxymethyl cellulose/hydromagnesite stromatolite bio-nanocomposite", CELLULOSE, 2022
dc.identifier.issn0969-0239
dc.identifier.othervv_1032021
dc.identifier.otherav_3321a970-c35e-48b8-bf69-41416ebe1409
dc.identifier.urihttp://hdl.handle.net/20.500.12627/182225
dc.identifier.urihttps://avesis.istanbul.edu.tr/api/publication/3321a970-c35e-48b8-bf69-41416ebe1409/file
dc.identifier.urihttps://doi.org/10.1007/s10570-022-04522-9
dc.description.abstractCurrently, researchers are focusing on the development of nano-additive preservatives during the worldwide COVID-19 pandemic. This research aimed to constitute a small sized preservative nano-formulation which emerges from the biopolymer carboxymethyl cellulose (a green stabilizing agent) and hydromagnesite stromatolite (a fossilized natural additive). In this study, we investigated the optimization of the experimental design of carboxymethyl cellulose/hydromagnesite stromatolite (CMC/HS) bio-nanocomposites using a green and one-step sonochemical method at room temperature. In addition, we constructed a mathematical model which relates the intrinsic viscosity with all operating variables, and we carried out statistical error analysis to assess the validity of the proposed model. The characterization and chemical functional groups of CMC/HS bio-nanocomposites were determined by different advanced techniques such as SEM, HRTEM, DLS, FTIR, XRD, and BET. The challenge test was used to show the preservative efficacy of CMC/HS bio-nanocomposites against Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli, Candida albicans, and Aspergillus brasiliensis. The 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltrazolium bromide (MTT) assay was performed on L929 cells to evaluate the in vitro cytotoxicity of CMC/HS bio-nanocomposites. According to the results, we showed that the synthesized CMC/HS bio-nanocomposites have no cytototoxic effects on L929 fibroblast cells and could be considered to be an alternative green nano-additive preservative against pathogenic microorganisms.
dc.language.isoeng
dc.subjectFizikokimya
dc.subjectPolimer Karakterizasyonu
dc.subjectTemel Bilimler
dc.subjectMühendislik ve Teknoloji
dc.subjectPolymers and Plastics
dc.subjectChemistry (miscellaneous)
dc.subjectGeneral Materials Science
dc.subjectGeneral Chemistry
dc.subjectPhysical Sciences
dc.subjectTemel Bilimler (SCI)
dc.subjectTekstil Mühendisliği ve Teknolojisi
dc.subjectPOLİMER BİLİMİ
dc.subjectMALZEME BİLİMİ, TEKSTİL
dc.subjectMühendislik, Bilişim ve Teknoloji (ENG)
dc.subjectMalzeme Bilimi
dc.subjectMALZEME BİLİMİ, KAĞIT & AHŞAP
dc.subjectKimya
dc.titleCharacterization, optimization, and evaluation of preservative efficacy of carboxymethyl cellulose/hydromagnesite stromatolite bio-nanocomposite
dc.typeMakale
dc.relation.journalCELLULOSE
dc.contributor.departmentİstanbul Üniversitesi-Cerrahpaşa , Mühendislik Fakültesi , Kimya Bölümü
dc.contributor.firstauthorID3404128


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