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dc.contributor.authorMERAL, İSMAİL
dc.contributor.authorÜSTÜNOVA, SAVAŞ
dc.contributor.authorKILIÇ, AYSU
dc.contributor.authorBulut, Huri
dc.contributor.authorGurel-Gurevin, Ebru
dc.contributor.authorERİŞ, ALİ HİKMET
dc.date.accessioned2022-07-04T16:12:58Z
dc.date.available2022-07-04T16:12:58Z
dc.identifier.citationÜSTÜNOVA S., KILIÇ A., Bulut H., Gurel-Gurevin E., ERİŞ A. H. , MERAL İ., "Impaired memory by hippocampal oxidative stress in rats exposed to 900 MHz electromagnetic fields is ameliorated by thymoquinone", TOXICOLOGICAL AND ENVIRONMENTAL CHEMISTRY, 2022
dc.identifier.issn0277-2248
dc.identifier.otherav_d9340aac-3667-438f-908d-32fec222f114
dc.identifier.othervv_1032021
dc.identifier.urihttp://hdl.handle.net/20.500.12627/184926
dc.identifier.urihttps://doi.org/10.1080/02772248.2022.2051509
dc.description.abstractThe protective effects of thymoquinone on learning and memory abilities and on hippocampal oxidative stress in rats exposed to 900 MHz electromagnetic field radiation at s strength of 6.0 +/- 0.5 V/m for 1 h on each of 15 days was studied. Thymoquinone-treatment (10 mg/kg/day) of radiation-exposed rats resulted in better performance than that of radiation-exposed rats not receiving thymoquinone. Electromagnetic field-exposure led to increased hippocampal superoxide dismutase, glutathione peroxidase, and malondialdehyde levels and to lowered brain-derived neurotrophic factor level; thymoquinone treatment ameliorated all four parameters. Also, in the electromagnetic field-exposed group, N-methyl-D-aspartate receptor expression decreased, and gamma-aminobutyric-acid alpha receptor expression increased, which was reversed by thymoquinone treatment. In conclusion, treatment with the thymoquinone ameliorated the impact of the exposure to EMF and provided a hint on the mechanism involving oxidative stress.
dc.language.isoeng
dc.subjectTarım ve Çevre Bilimleri (AGE)
dc.subjectTOKSİKOLOJİ
dc.subjectFarmakoloji ve Toksikoloji
dc.subjectYaşam Bilimleri (LIFE)
dc.subjectSağlık Bilimleri
dc.subjectEczacılık
dc.subjectMeslek Bilimleri
dc.subjectFarmasötik Toksikoloji
dc.subjectTarımsal Bilimler
dc.subjectÇevre Mühendisliği
dc.subjectYaşam Bilimleri
dc.subjectTemel Bilimler
dc.subjectMühendislik ve Teknoloji
dc.subjectNature and Landscape Conservation
dc.subjectEnvironmental Science (miscellaneous)
dc.subjectLife Sciences
dc.subjectAquatic Science
dc.subjectÇevre / Ekoloji
dc.subjectToxicology
dc.subjectPhysical Sciences
dc.subjectHealth, Toxicology and Mutagenesis
dc.subjectPharmacology, Toxicology and Pharmaceutics (miscellaneous)
dc.subjectÇEVRE BİLİMLERİ
dc.titleImpaired memory by hippocampal oxidative stress in rats exposed to 900 MHz electromagnetic fields is ameliorated by thymoquinone
dc.typeMakale
dc.relation.journalTOXICOLOGICAL AND ENVIRONMENTAL CHEMISTRY
dc.contributor.departmentBezmiâlem Vakıf Üniversitesi , Tıp Fakültesi , Temel Tıp Bilimleri Bölümü
dc.contributor.firstauthorID3401908


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