Vitamin and Herbal Supplements in Parkinson Disease

Abstract

Parkinson's disease (PD) is a degenerative process affecting the basal ganglia, mainly substantia nigra and other brainstem pigmented neurons, and is manifested by dopamine deficiency in the brain. The main clinical findings are rest tremor, bradykinesia, rigidity and posterior reflex disorder. Studies indicate that approximately 1% of the population over 65 years of age is involved in this disease. Today, the cause of nigral degeneration responsible for the development of this disease is unknown. However, considering the studies, it can be seen that hereditary predisposition, environmental toxins and aging play an important role in this process and especially multifactorial causes are prominent. PD treatment is lifelong and its main treatment is the substitution of dopamine hormone and reduction of symptoms. Here, vitamins and herbal supplements that play a role in the prevention and treatment of Parkinson's are briefly reviewed.