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dc.contributor.authorCampi, Riccardo
dc.contributor.authorCarbonara, Umberto
dc.contributor.authorRoussel, Eduard
dc.contributor.authorAmparore, Daniele
dc.contributor.authorBertolo, Riccardo
dc.contributor.authorMarchioni, Michele
dc.contributor.authorMuselaers, Stijn
dc.contributor.authorPavan, Nicola
dc.contributor.authorPecoraro, Angela
dc.contributor.authorBeuselinck, Benoit
dc.contributor.authorPedrosa, Ivan
dc.contributor.authorFetzer, David
dc.contributor.authorAlbersen, Maarten
dc.contributor.authorERDEM, Selçuk
dc.contributor.authorIngels, Alexandre
dc.contributor.authorKARA, ÖNDER
dc.contributor.authorMarandino, Laura
dc.date.accessioned2022-07-04T16:34:58Z
dc.date.available2022-07-04T16:34:58Z
dc.date.issued2022
dc.identifier.citationRoussel E., Campi R., Amparore D., Bertolo R., Carbonara U., ERDEM S., Ingels A., KARA Ö., Marandino L., Marchioni M., et al., "Expanding the Role of Ultrasound for the Characterization of Renal Masses", Journal of Clinical Medicine, cilt.11, sa.4, 2022
dc.identifier.issn2077-0383
dc.identifier.othervv_1032021
dc.identifier.otherav_ecb4fe62-7861-456f-9c43-8a6522b8828b
dc.identifier.urihttp://hdl.handle.net/20.500.12627/185247
dc.identifier.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85124979848&origin=inward
dc.identifier.urihttps://doi.org/10.3390/jcm11041112
dc.description.abstract© 2022 by the authors. Licensee MDPI, Basel, Switzerland.Background The incidental detection of renal masses has been steadily rising. As a significant proportion of renal masses that are surgically treated are benign or indolent in nature, there is a clear need for better presurgical characterization of renal masses to minimize unnecessary harm. Ultrasound is a widely available and relatively inexpensive real-time imaging technique, and novel ultrasound-based applications can potentially aid in the non-invasive characterization of renal masses. Evidence acquisition: We performed a narrative review on novel ultrasound-based techniques that can aid in the non-invasive characterization of renal masses. Evidence synthesis: Contrast-enhanced ultrasound (CEUS) adds significant diagnostic value, particularly for cystic renal masses, by improving the characterization of fine septations and small nodules, with a sensitivity and specificity comparable to magnetic resonance imaging (MRI). Additionally, the performance of CEUS for the classification of benign versus malignant renal masses is comparable to that of computed tomography (CT) and MRI, although the imaging features of different tumor subtypes overlap significantly. Ultrasound molecular imaging with targeted contrast agents is being investigated in preclinical research as an addition to CEUS. Elastography for the assessment of tissue stiffness and micro-Doppler imaging for the improved detection of intratumoral blood flow without the need for contrast are both being investigated for the characterization of renal masses, though few studies have been conducted and validation is lacking. Conclusions: Several novel ultrasound-based techniques have been investigated for the non-invasive characterization of renal masses. CEUS has several advantages over traditional grayscale ultrasound, including the improved characterization of cystic renal masses and the potential to differentiate benign from malignant renal masses to some extent. Ultrasound molecular imaging offers promise for serial disease monitoring and the longitudinal assessment of treatment response, though this remains in the preclinical stages of development. While elastography and emerging micro-Doppler techniques have shown some encouraging applications, they are currently not ready for widespread clinical use.
dc.language.isoeng
dc.subjectSağlık Bilimleri
dc.subjectGeneral Medicine
dc.subjectHealth Sciences
dc.subjectTıp
dc.subjectTIP, GENEL & İÇECEK
dc.subjectKlinik Tıp
dc.subjectKlinik Tıp (MED)
dc.subjectTemel Tıp Bilimleri
dc.titleExpanding the Role of Ultrasound for the Characterization of Renal Masses
dc.typeMakale
dc.relation.journalJournal of Clinical Medicine
dc.contributor.departmentUniversity of G. d'Annunzio Chieti and Pescara , ,
dc.identifier.volume11
dc.identifier.issue4
dc.contributor.firstauthorID3395171


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