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dc.contributor.authorAltay, Ali Yılmaz
dc.contributor.authorYalçın, Özben
dc.contributor.authorAydın, Emine
dc.contributor.authorBağcı, Helin
dc.contributor.authorŞahin, Orhan
dc.date.accessioned2023-02-21T07:41:18Z
dc.date.available2023-02-21T07:41:18Z
dc.date.issued2022
dc.identifier.citationŞahin O., Altay A. Y., Aydın E., Bağcı H., Yalçın Ö., "Effect of asymptomatic COVID-19 infection on the placenta in the third trimester of pregnancy: A prospective case-control study Term gebeliklerde asemptomatik COVID-19’un plasentaya etkisi: Prospektif olgu-kontrol çalışması", Turkish Journal of Obstetrics and Gynecology, cilt.19, sa.3, ss.178-186, 2022
dc.identifier.issn2149-9330
dc.identifier.othervv_1032021
dc.identifier.otherav_0b3fbaee-ac00-4411-bdc2-bc5dc4ccb6a4
dc.identifier.urihttp://hdl.handle.net/20.500.12627/186020
dc.identifier.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85138740867&origin=inward
dc.identifier.urihttps://doi.org/10.4274/tjod.galenos.2022.94984
dc.description.abstract© 2022 by Turkish Society of Obstetrics and Gynecology.Objective: To clarify the effect of asymptomatic coronaviruse disease-2019 (COVID-19) positivity on the placenta in the third trimester of pregnancy. Materials and Methods: This prospective, case-control study included 30 pregnant women diagnosed with asymptomatic COVID-19 between April 30, 2021 and July 20, 2021 who delivered after the 34th gestational week, and a control group of 30 pregnant women without COVID-19, who delivered between April 2021 and July 2021, matched to the study group regarding age, gestational age and body mass index. Outcomes were compared in terms of demographic characteristics, serum blood outcomes, neonatal results, complications and placental histopathological findings. Results: The mean age of the study population was 28.8 years and the mean gestational week was 38.2 weeks. The C-reactive protein levels (38.2 mg/L vs 5.8 mg/L, p=0.001) and ferritin levels (266.4 μg/L and 40.5 μg/L, p=0.001) were significantly higher in the COVID-19-positive pregnant women. The lymphocyte level was significantly higher in the non-COVID-19 pregnant women (p=0.040). Mural hypertrophy was determined at a significantly higher rate in COVID-positive pregnant women (83.3% vs 30.0%, p=0.001). Multivariate regression analysis showed that only COVID-19 positivity increased the presence of mural hypertrophy in pregnant women with asymptomatic COVID-19 (4.716-fold, 95% confidence interval=1.012-22.251). Conclusion: The results of this study demonstrated that asymptomatic COVID-19 had no significant effect on pregnancy and neonatal complications. However, mural hypertrophy in the placenta was found at a significantly higher rate in pregnant women with asymptomatic COVID-19.
dc.language.isoeng
dc.subjectDoğum ve Jinekoloji
dc.subjectKlinik Tıp (MED)
dc.subjectKlinik Tıp
dc.subjectKADIN HASTALIKLARI & DOĞUM
dc.subjectTıp
dc.subjectCerrahi Tıp Bilimleri
dc.subjectKadın Hastalıkları ve Doğum
dc.subjectSağlık Bilimleri
dc.titleEffect of asymptomatic COVID-19 infection on the placenta in the third trimester of pregnancy: A prospective case-control study Term gebeliklerde asemptomatik COVID-19’un plasentaya etkisi: Prospektif olgu-kontrol çalışması
dc.typeMakale
dc.relation.journalTurkish Journal of Obstetrics and Gynecology
dc.contributor.departmentSisli Hamidiye Etfal Training and Research Hospital , ,
dc.identifier.volume19
dc.identifier.issue3
dc.identifier.startpage178
dc.identifier.endpage186
dc.contributor.firstauthorID4247954


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