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dc.contributor.authorAlbayrak, Eda
dc.contributor.authorBüyükcam, Ayşe
dc.contributor.authorSütçü, Murat
dc.contributor.authorSali, Enes
dc.contributor.authorBozdemir, Şefika Elmas
dc.contributor.authorKara, Manolya
dc.contributor.authorİlarslan, Eda Çullas
dc.contributor.authorKaya, Cemil
dc.contributor.authorKarakaşlılar, Sabahat
dc.contributor.authorSönmez, Gülsüm
dc.contributor.authorKara, Soner Sertan
dc.contributor.authorBedir, Tuğba
dc.contributor.authorKARA, ATEŞ
dc.contributor.authorKara, Tuğçe Tural
dc.contributor.authorÇelebi, Solmaz
dc.contributor.authorÖz, Fatma Nur
dc.contributor.authorKarbuz, Adem
dc.contributor.authorSomer, Ayper
dc.contributor.authorAlabaz, Derya
dc.contributor.authorTezer, Hasan
dc.contributor.authorÖzdemir, Halil
dc.contributor.authorÇiftçi, Ergin
dc.date.accessioned2023-02-21T09:52:47Z
dc.date.available2023-02-21T09:52:47Z
dc.identifier.citationKARA A., Büyükcam A., Sütçü M., Sali E., Bozdemir Ş. E., Kara M., İlarslan E. Ç., Kaya C., Karakaşlılar S., Sönmez G., et al., "The effectiveness of topical 1% lidocaine with systemic oral analgesics for ear pain with acute otitis media", International Journal of Pediatric Otorhinolaryngology, cilt.156, 2022
dc.identifier.issn0165-5876
dc.identifier.othervv_1032021
dc.identifier.otherav_3792064b-7435-40f6-8a62-d9e31693cb90
dc.identifier.urihttp://hdl.handle.net/20.500.12627/187894
dc.identifier.urihttps://doi.org/10.1016/j.ijporl.2022.111116
dc.identifier.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85126658132&origin=inward
dc.description.abstract© 2022Background: Acute otitis media (AOM) is one of the most common childhood infections. Ear pain, the main symptom of AOM, results in parents frequently seeking medical assistance for their children. The aim of this study was to compare the effectiveness of topical 1% lidocaine ear drops administered with oral analgesics with that of oral analgesics alone. Methods: This multicenter randomized, open-labeled study was conducted at 15 centers with 184 pediatric AOM patients with bilateral ear pain (aged 1–5 years) between May 1, 2016, and June 31, 2018. All patients received oral paracetamol or ibuprofen and topical 1% lidocaine, which was administered to each ear according to the randomization list. The ear pain score was evaluated within 48 h using the Face, Legs, Activity, Cry, and Consolability (FLACC) scale, and the patients were followed up for 10 days. Results: The median age was 31.8 months (min–max, 12–84.2 months). Of those patients enrolled, 22.3% received paracetamol, and 24.5% received paracetamol with lidocaine ear drops; 23.4% received ibuprofen, and 29.9% received ibuprofen with lidocaine ear drops. Lower pain scores were significantly measured at baseline and 10th minutes by a reduction 25% (RR 13.64, 95% CI 4.47–41.63, p = 0.001, RR 0.14, 95% CI 0.06–0.35, p = 0.001) and 50% (RR 4.76, 95% CI 1.63–13.87, p = 0.004, RR 0.14, 95% CI 0.05–0.4, p = 0.001) in the paracetamol and lidocaine versus paracetamol groups and the ibuprofen and lidocaine versus ibuprofen groups, respectively. No serious side effects were evident during follow-up. Conclusion: This randomized study suggests that topical 1% lidocaine ear drops with paracetamol or ibuprofen seems to provide effective and rapid relief for children presenting with ear pain attributed to AOM.
dc.language.isoeng
dc.subjectKulak Burun Boğaz
dc.subjectSağlık Bilimleri
dc.subjectPediatri, Perinatoloji ve Çocuk Sağlığı
dc.subjectÇocuk Sağlığı ve Hastalıkları
dc.subjectCerrahi Tıp Bilimleri
dc.subjectDahili Tıp Bilimleri
dc.subjectTıp
dc.subjectPEDİATRİ
dc.subjectKULAK BURUN BOĞAZ
dc.subjectKlinik Tıp
dc.subjectKlinik Tıp (MED)
dc.titleThe effectiveness of topical 1% lidocaine with systemic oral analgesics for ear pain with acute otitis media
dc.typeMakale
dc.relation.journalInternational Journal of Pediatric Otorhinolaryngology
dc.contributor.departmentHacettepe Üniversitesi , Tıp Fakültesi (Türkçe) , Dahili Tıp Bilimleri Bölümü
dc.identifier.volume156
dc.contributor.firstauthorID4242695


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