Show simple item record

dc.contributor.authorAŞICIOĞLU, FARUK
dc.contributor.authorERKAN, ITIR
dc.contributor.authorRAYİMOĞLU, Gülten
dc.contributor.authorCanpolat, Elif
dc.contributor.authorOzturk, Onur
dc.contributor.authorYÜKSELOĞLU, EMEL HÜLYA
dc.contributor.authorÇAVUŞ YONAR, FATMA
dc.contributor.authorKARATAŞ, ÖMER
dc.date.accessioned2023-10-10T11:47:46Z
dc.date.available2023-10-10T11:47:46Z
dc.date.issued2023
dc.identifier.citationYÜKSELOĞLU E. H., ÇAVUŞ YONAR F., KARATAŞ Ö., RAYİMOĞLU G., AŞICIOĞLU F., Canpolat E., Ozturk O., ERKAN I., "Population Data and Internal Validation of the 21 Short Tandem Repeat Loci in Turkish Population", PAKISTAN JOURNAL OF ZOOLOGY, sa.2, ss.501-512, 2023
dc.identifier.issn0030-9923
dc.identifier.othervv_1032021
dc.identifier.otherav_1a62b53d-54d7-4f02-ac4d-8e0c98976870
dc.identifier.urihttp://hdl.handle.net/20.500.12627/189914
dc.identifier.urihttps://avesis.istanbul.edu.tr/api/publication/1a62b53d-54d7-4f02-ac4d-8e0c98976870/file
dc.identifier.urihttps://doi.org/10.17582/journal.pjz/20210803110808
dc.description.abstractThe purpose of this study was to identify paternity relations and increase the likelihood success in DNA identification of biological samples found in mass disasters and criminal events by using the 6-dye GlobalFilerTM amplification kit with 21 autosomal STR loci in our laboratory for validation purpose and routine use. In this regard, swab samples from different regions of Turkey (n=350) were collected and studied. The validation of the GlobalFilerTM Amplification Kit was carried out in accordance with the guidelines published by the Scientific Working Group on DNA Analysis Methods (SWGDAM). Our study was conducted to show the efficacy and performance of the kit for sensitivity, specificity, limit of detection, dynamic range, limit of quantification, stochastic threshold study, reproducibility and repeatability, mixture and contamination study parameters. Validation parameters and population genetics data were calculated by using Arlequin v 3.5.2.2 version. According to our results, SE33 (PM=0.014) locus showed the greatest power of discrimination and TPOX (PM=0.132) has the least power of discrimination power in Turkish population. Combined power of exclusion and combined power of discrimination were calculated as 99.99999963% and 99.99999999%, respectively. In addition, allelic frequencies from our study were compared to previously published population data of Iraq, Saud Arabia, China (Han), USA (Cauc), Iran, Afghan, Azerbaijan, Romania, and South Africa. The study revealed that there was a significant difference between Turkish and South Africa (0.1198) population and no difference was observed for Azerbaijan (0.0097) population.
dc.language.isoeng
dc.subjectYaşam Bilimleri
dc.subjectSağlık Bilimleri
dc.subjectHayvan Bilimi ve Zooloji
dc.subjectKüçük hayvanlar
dc.subjectTarımsal Bilimler
dc.subjectTarım ve Çevre Bilimleri (AGE)
dc.subjectBitki ve Hayvan Bilimleri
dc.subjectZOOLOJİ
dc.titlePopulation Data and Internal Validation of the 21 Short Tandem Repeat Loci in Turkish Population
dc.typeMakale
dc.relation.journalPAKISTAN JOURNAL OF ZOOLOGY
dc.contributor.departmentİstanbul Üniversitesi-Cerrahpaşa , Adli Tıp Ve Adli Bilimler Enstitüsü ,
dc.identifier.issue2
dc.identifier.startpage501
dc.identifier.endpage512
dc.contributor.firstauthorID4310125


Files in this item

FilesSizeFormatView

There are no files associated with this item.

This item appears in the following Collection(s)

Show simple item record