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dc.contributor.authorDÖNMEZ, LEVENT
dc.contributor.authorÖĞÜNÇ, MERAL DİLARA
dc.contributor.authorYAZISIZ, HATİCE
dc.contributor.authorKuskucu, Mert A.
dc.contributor.authorMidilli, Kenan
dc.contributor.authorKOYUNCU ÖZYURT, ÖZLEM
dc.contributor.authorCetinkaya, Ozgul
dc.contributor.authorÖZHAK, BETİL
dc.contributor.authorÖNGÜT, GÖZDE
dc.contributor.authorTURHAN, ÖZGE
dc.date.accessioned2023-10-10T12:30:05Z
dc.date.available2023-10-10T12:30:05Z
dc.date.issued2023
dc.identifier.citationKOYUNCU ÖZYURT Ö., Cetinkaya O., ÖZHAK B., ÖNGÜT G., TURHAN Ö., YAZISIZ H., DÖNMEZ L., Kuskucu M. A., Midilli K., ÖĞÜNÇ M. D., "Evaluation of the BD Phoenix CPO Detect Test for detection of carbapenemase-producing Enterobacterales", FUTURE MICROBIOLOGY, sa.7, ss.399-405, 2023
dc.identifier.issn1746-0913
dc.identifier.othervv_1032021
dc.identifier.otherav_2177f1a1-72f0-4f78-b3d0-dcbc3c531099
dc.identifier.urihttp://hdl.handle.net/20.500.12627/190114
dc.identifier.urihttps://doi.org/10.2217/fmb-2022-0071
dc.description.abstractPlain language summaryEnterobacterales are a type of bacteria that usually live harmlessly in the gut of humans. However, if the bacteria get access to the bladder or bloodstream, they can cause infection. Carbapenemase-producing Enterobacterales (CPE) are a type of bacteria that can cause carbapenem antibiotic-resistant infections, a group of powerful antibiotics. The rapid spread of CPE will pose an increasing threat to public health and medical treatment practices; therefore, rapid detection of CPE is crucial. This study assessed the performance of the BD Phoenix CPO Detect Test for the detection of carbapenemase-producing Enterobacterales. The BD Phoenix CPO Detect Test offers both the detection of carbapenemase production and antimicrobial susceptibility testing simultaneously and can be clinically useful for determining possible treatment options. Aims: This study aimed to evaluate the performance of the BD Phoenix CPO Detect Test (BD Diagnostic Systems) for the detection and classification of carbapenemase-mediated carbapenem resistance. Methods: A total of 447 Enterobacterales strains were included in the study. All strains were tested with the BD Phoenix CPO Detect Test and the modified carbapenem inactivation method. Results: Carbapenemase production was detected in 157 of 159 carbapenemase producers, including 95.7% of class B and 99.2% of class D isolates using the BD Phoenix CPO Detect Test. BD Phoenix CPO Detect has a sensitivity of 98.7% and a specificity of 95.5% in detecting carbapenemase production. Conclusion: The classification of OXA-48 and class B carbapenemases, the most common carbapenemases circulating in Turkey, was highly accurate.
dc.language.isoeng
dc.subjectMikrobiyoloji
dc.subjectYaşam Bilimleri (LIFE)
dc.subjectYaşam Bilimleri
dc.subjectTemel Bilimler
dc.titleEvaluation of the BD Phoenix CPO Detect Test for detection of carbapenemase-producing Enterobacterales
dc.typeMakale
dc.relation.journalFUTURE MICROBIOLOGY
dc.contributor.departmentAkdeniz Üniversitesi , Tıp Fakültesi , Temel Tıp Bilimleri Bölümü
dc.identifier.issue7
dc.identifier.startpage399
dc.identifier.endpage405
dc.contributor.firstauthorID4314091


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