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dc.contributor.authorALHAJ, Safa
dc.contributor.authorCIVILIBAL, Mahmut
dc.contributor.authorCelkan, Tülin Tıraje
dc.contributor.authorElicevik, Mehmet
dc.date.accessioned2021-03-03T08:41:56Z
dc.date.available2021-03-03T08:41:56Z
dc.date.issued2007
dc.identifier.citationCelkan T. T. , ALHAJ S., CIVILIBAL M., Elicevik M., "Control of bleeding associated with hemophagocytic syndrome in children: An audit of the clinical use of recombinant activated factor VII", PEDIATRIC HEMATOLOGY AND ONCOLOGY, cilt.24, sa.2, ss.117-121, 2007
dc.identifier.issn0888-0018
dc.identifier.otherav_18e9243b-4e05-44fd-b846-4bee288c9582
dc.identifier.othervv_1032021
dc.identifier.urihttp://hdl.handle.net/20.500.12627/22069
dc.identifier.urihttps://doi.org/10.1080/08880010601094102
dc.description.abstractThis paper presents 2 cases of hemophagocytic lymphohistiocytosis (HLH) in whom recombinant factor VIIa ( rFVIIa) was used for the management of hemorrhage. Both patients were diagnosed as HLH and were bleeding from the gut, which could not be controlled. Patients received rFVIIa at total doses of between 90 and 180 mu g/kg body weight. Hemostatic affect was achieved in both of the patients but lasted only a short time. The response was achieved after 1 h of administration of rFVIIa, lasting for 24 h. The use of rFVIIa was well tolerated. These 2 patients suggest that rFVIIa is a beneficial agent in the management of hemorrhage in patients with HLH, although for a permanent homeostasis the control of primary disease is essential.
dc.language.isoeng
dc.subjectDahili Tıp Bilimleri
dc.subjectOnkoloji
dc.subjectONKOLOJİ
dc.subjectKlinik Tıp
dc.subjectKlinik Tıp (MED)
dc.subjectHEMATOLOJİ
dc.subjectPEDİATRİ
dc.subjectTıp
dc.subjectSağlık Bilimleri
dc.subjectHematoloji
dc.subjectÇocuk Sağlığı ve Hastalıkları
dc.subjectİç Hastalıkları
dc.titleControl of bleeding associated with hemophagocytic syndrome in children: An audit of the clinical use of recombinant activated factor VII
dc.typeMakale
dc.relation.journalPEDIATRIC HEMATOLOGY AND ONCOLOGY
dc.contributor.departmentMarmara Üniversitesi , ,
dc.identifier.volume24
dc.identifier.issue2
dc.identifier.startpage117
dc.identifier.endpage121
dc.contributor.firstauthorID32600


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