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Melatonin Expresses Powerful Anti-inflammatory and Antioxidant Activities Resulting in Complete Improvement of Acetic-Acid-Induced Colitis in Rats

dc.contributor.authorTahan, Gulgun
dc.contributor.authorAktolga, Serdal
dc.contributor.authorMarongiu, Fabio
dc.contributor.authorCetinkaya, Ali
dc.contributor.authorGramignoli, Roberto
dc.contributor.authorDorko, Kenneth
dc.contributor.authorTahan, Veysel
dc.date.accessioned2021-03-03T10:42:25Z
dc.date.available2021-03-03T10:42:25Z
dc.date.issued2011
dc.identifier.citationTahan G., Gramignoli R., Marongiu F., Aktolga S., Cetinkaya A., Tahan V., Dorko K., "Melatonin Expresses Powerful Anti-inflammatory and Antioxidant Activities Resulting in Complete Improvement of Acetic-Acid-Induced Colitis in Rats", DIGESTIVE DISEASES AND SCIENCES, cilt.56, sa.3, ss.715-720, 2011
dc.identifier.issn0163-2116
dc.identifier.otherav_2428d492-3880-40f0-a23d-e98bc0705928
dc.identifier.othervv_1032021
dc.identifier.urihttp://hdl.handle.net/20.500.12627/29209
dc.identifier.urihttps://doi.org/10.1007/s10620-010-1364-5
dc.description.abstractIncreased free-radical production, decreased antioxidant capacity, and excessive inflammation are well-known features in the pathogenesis of inflammatory bowel disease. Melatonin is a powerful antioxidant and a scavenger of hydroxyl radicals. Melatonin has also been shown to have anti-inflammatory activities in tissues. Our study objective is to investigate the effects of melatonin on tissue inflammatory activities using an ulcerative colitis (UC) model induced by acetic acid (AA) in rats.
dc.language.isoeng
dc.subjectSağlık Bilimleri
dc.subjectDahili Tıp Bilimleri
dc.subjectİç Hastalıkları
dc.subjectGastroenteroloji-(Hepatoloji)
dc.subjectTıp
dc.subjectKlinik Tıp (MED)
dc.subjectKlinik Tıp
dc.subjectGASTROENTEROLOJİ VE HEPATOLOJİ
dc.titleMelatonin Expresses Powerful Anti-inflammatory and Antioxidant Activities Resulting in Complete Improvement of Acetic-Acid-Induced Colitis in Rats
dc.typeMakale
dc.relation.journalDIGESTIVE DISEASES AND SCIENCES
dc.contributor.departmentİstanbul Üniversitesi , ,
dc.identifier.volume56
dc.identifier.issue3
dc.identifier.startpage715
dc.identifier.endpage720
dc.contributor.firstauthorID199674


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