TOLERABILITY OF NIMESULIDE IN PATIENTS WITH HISTORIES OF ADVERSE REACTIONS TO ACETYLSALICYLIC ACID AND NONSTEROIDAL ANTI-INFLAMMATORY DRUGS

Abstract

Objective: Analgesic and anti-inflammatory treatment in patients with a positive history of ASA (acetyl salicylic acid) /NSAID (non-steroidal anti-inflammatory drugs) intolerance is a significant problem in clinical practice. Therefore, there is a need to identify an alternative drug that is safe and reliable. Our aim was to determine the safety of nimesulide, a preferential COX-2 inhibitor.