Spectral Characterization and Antibacterial Effect of 2-Methyl-6-(5-H/Me/Cl/NO2-1H-Benzimidazol-2-yl)-Phenols and Some Transition Metal Complexes

Abstract

2-Methyl-6-(5-H/methyl/chloro/nitro-1H-benzimidazol-2-yl)-phenols (HLx : x = 1-4) ligands and HL1 complexes with Fe(NO3)(3), Cu(NO3)(2), AgNO3, Zn(NO3)(2) have been synthesized and characterized. The structures of the compounds were confirmed on the basis of elemental analysis, molar conductivity, magnetic moment, FT-IR, H-1- and C-13-NMR. Antibacterial activity of the free ligands, their hydrochloride salts and the complexes were evaluated using the disk diffusion method in dimethyl sulfoxide as well as the minimum inhibitory concentration dilution method, against nine bacteria. While HL1 ligand has not any activity, it's Ag(I) complex show antibacterial effect toward almost to all the bacteria. Zn(II) complex has antibacterial effect on especially K. pneumoniae, S. epidermidis and S. aureus bacteria.