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dc.contributor.authorArun, Seckin Serdar
dc.contributor.authorYilmaz, Ozge Turna
dc.contributor.authorKirsan, Ismail
dc.contributor.authorAtes, Atila
dc.contributor.authorEnginler, Sinem Ozlem
dc.contributor.authorGultekin, Guldal Inal
dc.contributor.authorDemirtas, Berjan
dc.contributor.authorBamac, Ozge Erdogan
dc.contributor.authorKarabulut, Tugba Seval Fatma Toydemir
dc.date.accessioned2021-03-03T12:48:32Z
dc.date.available2021-03-03T12:48:32Z
dc.date.issued2016
dc.identifier.citationKarabulut T. S. F. T. , Gultekin G. I. , Ates A., Yilmaz O. T. , Enginler S. O. , Kirsan I., Bamac O. E. , Arun S. S. , Demirtas B., "Effects of Pyometra on Some Oxidative Stress Parameters, Inflammatory Mediators and Neutrophil Segmentation in Bitches", KAFKAS UNIVERSITESI VETERINER FAKULTESI DERGISI, cilt.22, sa.6, ss.837-846, 2016
dc.identifier.issn1300-6045
dc.identifier.othervv_1032021
dc.identifier.otherav_30351f3b-a542-4ebe-87b6-e1e3619ef453
dc.identifier.urihttp://hdl.handle.net/20.500.12627/36899
dc.identifier.urihttps://doi.org/10.9775/kvfd.2016.15443
dc.description.abstractPyometra is characterized by uterine bacterial infection with the accumulation of pus in the uterus often initiates systemic inflammation in the body and may lead to multiple organ dysfunction syndrome (MODS). The main objectives of this study is to evaluate C-reactive protein (CRP), tumour necrosis factor-alpha (TNF-alpha), interleukin-6 (IL-6), superoxide dismutase (SOD), catalase (CAT), and thiobarbituric acid-reactive substances (TBARS) in bitches with pyometra and control bitches to explore the possible variety between the groups to detect the morbidity of the disease and contribution of these parameters in the condition of MODS. All bitches underwent ovariohysterectomy (OVH) and blood sampling was performed just before and after 15 days of the surgery. TNF-alpha, CRP, and IL-6 levels were significantly higher in pyometra group before the OVH (P<0.05, P<0.001, P<0.001, respectively), and CRP and IL-6 levels were significantly high after 15 days of OVH (P<0.001, P<0.05, respectively). Two-segmented neutrophils were significantly lower in pyometra group before (P<0.05) and after OVH (P<0.01). It is revealed that with this study, CRP and IL-6 could be used for inflammation detection when leucocyte number was normal in operated bitches with pyometra. Oxidative stress was not apparent in bitches with pyometra. Also, platelet (PLT) level and neutrophil segmentation index (NSI) might be good indicators to identify the chronic phase and the severity of the disease and risk of disseminated intravascular coagulation (DIC) in bitches with pyometra.
dc.language.isoeng
dc.subjectTarım ve Çevre Bilimleri (AGE)
dc.subjectVeteriner Bilimleri
dc.subjectVETERİNERLİK BİLİMLERİ
dc.subjectBitki ve Hayvan Bilimleri
dc.subjectSağlık Bilimleri
dc.subjectTarımsal Bilimler
dc.titleEffects of Pyometra on Some Oxidative Stress Parameters, Inflammatory Mediators and Neutrophil Segmentation in Bitches
dc.typeMakale
dc.relation.journalKAFKAS UNIVERSITESI VETERINER FAKULTESI DERGISI
dc.contributor.departmentİstanbul Üniversitesi , ,
dc.identifier.volume22
dc.identifier.issue6
dc.identifier.startpage837
dc.identifier.endpage846
dc.contributor.firstauthorID236321


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