Preclinical validation of a monochrome real-time multiplex assay for translocations in childhood acute lymphoblastic leukemia
Date
2002Author
BHATIA, K
Sirma, Sema
EL SOLH, H
GUTIERREZ, MI
OZBEK, UĞUR
SIRAJ, AK
SAZAWAL, S
TIMSON, G
AL-NASSER, A
BHARGAVA, M
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Purpose: The purpose is to develop a real-time multiplex reverse transcription-PCR assay for detection and quantification of leukemia-specific chimeric transcripts that identify the genetic subgroups of acute lymphoblastic leukemias (ALLs) proposed by the WHO classification.
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