dc.contributor.author | Atci, Tuğba | |
dc.contributor.author | Baykal, Can | |
dc.date.accessioned | 2021-03-02T17:41:43Z | |
dc.date.available | 2021-03-02T17:41:43Z | |
dc.date.issued | 2020 | |
dc.identifier.citation | Atci T., Baykal C., "Efficacy of narrow-band ultraviolet-B therapy in patch-stage mycosis fungoides: A clinical study and review of the literature", Photodermatology Photoimmunology and Photomedicine, cilt.36, sa.4, ss.271-277, 2020 | |
dc.identifier.issn | 0905-4383 | |
dc.identifier.other | vv_1032021 | |
dc.identifier.other | av_349e0217-e803-4608-bbf9-794944e5342c | |
dc.identifier.uri | http://hdl.handle.net/20.500.12627/4272 | |
dc.identifier.uri | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85082054394&origin=inward | |
dc.identifier.uri | https://doi.org/10.1111/phpp.12547 | |
dc.description.abstract | © 2020 John Wiley & Sons A/S. Published by John Wiley & Sons LtdBackground/Purpose: We investigated the efficacy of narrow-band UVB in patch-stage MF and reviewed the literature to re-evaluate the role of this phototherapy method in early MF. Methods: Early-stage MF patients treated with narrow-band UVB were included. Number of narrow-band UVB treatment sessions, treatment duration, cumulative UV dose, clinical response results, side effects, duration of the remission period and relapse rate were evaluated. Results: Complete response rate was 86.7% in sixty patients with MF. Mean number of treatment sessions was 62.9 ± 15.1, treatment duration was 32.1 ± 10.7 weeks, and mean cumulative UV dose was 62.1 ± 41.9 J/cm2 in patients with complete response. Mean duration of remission was 10.3 ± 11.0 months, and relapse rate was 70% in a mean follow-up of 21.9 ± 16.4 months. Mild regional erythema (6.7%) and pruritus (8.3%) were main side effects. There were no significant differences between stage IA and stage IB patients in terms of treatment parameters and duration of remission period. Conclusions: Our study confirms that narrow-band UVB is effective for the management of the patch-stage MF without serious side effects. Extent of the skin lesions did not affect the efficacy of phototherapy. However, due to the short duration of remission, a further option such as an optimal maintenance therapy protocol should be considered. | |
dc.language.iso | eng | |
dc.subject | Klinik Tıp | |
dc.subject | Dermatoloji | |
dc.subject | Dahili Tıp Bilimleri | |
dc.subject | DERMATOLOJİ | |
dc.subject | Sağlık Bilimleri | |
dc.subject | Tıp | |
dc.subject | Klinik Tıp (MED) | |
dc.title | Efficacy of narrow-band ultraviolet-B therapy in patch-stage mycosis fungoides: A clinical study and review of the literature | |
dc.type | Makale | |
dc.relation.journal | Photodermatology Photoimmunology and Photomedicine | |
dc.contributor.department | İstanbul Üniversitesi , İstanbul Tıp Fakültesi , Dahili Tıp Bilimleri Bölümü | |
dc.identifier.volume | 36 | |
dc.identifier.issue | 4 | |
dc.identifier.startpage | 271 | |
dc.identifier.endpage | 277 | |
dc.contributor.firstauthorID | 2278692 | |