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Comparison of the effects of chronic intra-articular administration of tenoxicam, diclofenac, and methylprednisolone in healthy rats

dc.contributor.authorMidi, Ahmet
dc.contributor.authorPurisa, SEVİM
dc.contributor.authorAK, Dursun
dc.contributor.authorLacin, Berna
dc.contributor.authorBULUT, Guven
dc.contributor.authorORAK, Mehmet Mufit
dc.date.accessioned2021-03-03T14:33:23Z
dc.date.available2021-03-03T14:33:23Z
dc.date.issued2015
dc.identifier.citationORAK M. M. , AK D., Midi A., Lacin B., Purisa S., BULUT G., "Comparison of the effects of chronic intra-articular administration of tenoxicam, diclofenac, and methylprednisolone in healthy rats", ACTA ORTHOPAEDICA ET TRAUMATOLOGICA TURCICA, cilt.49, sa.4, ss.438-446, 2015
dc.identifier.issn1017-995X
dc.identifier.otherav_3a3b1233-20ec-4083-bf87-4fb7a2bf6a47
dc.identifier.othervv_1032021
dc.identifier.urihttp://hdl.handle.net/20.500.12627/43125
dc.identifier.urihttps://doi.org/10.3944/aott.2015.14.0312
dc.description.abstractObjective: Lyophilized drug manufacturing and intra-articular (IA) applications have increased to address gastrointestinal side effects resulting from chronic treatment with non-steroidal anti-inflammatory drugs (NSAIDs) for degenerative joint disease. Accordingly, we histologically examined joint and stomach tissues from rats to determine and compare the effects of long-term treatment with an IA corticosteroid (methylprednisolone acetate), lyophilized NSAID (tenoxicam), and non-lyophilized NSAID (diclofenac) following application to the knee joint.
dc.language.isoeng
dc.subjectOrtopedi ve Travmatoloji
dc.subjectCerrahi Tıp Bilimleri
dc.subjectSağlık Bilimleri
dc.subjectTıp
dc.subjectKlinik Tıp (MED)
dc.subjectKlinik Tıp
dc.subjectORTOPEDİ
dc.titleComparison of the effects of chronic intra-articular administration of tenoxicam, diclofenac, and methylprednisolone in healthy rats
dc.typeMakale
dc.relation.journalACTA ORTHOPAEDICA ET TRAUMATOLOGICA TURCICA
dc.contributor.departmentFatih Sultan Mehmet Training & Research Hospital , ,
dc.identifier.volume49
dc.identifier.issue4
dc.identifier.startpage438
dc.identifier.endpage446
dc.contributor.firstauthorID60581


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