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dc.contributor.authorIsik, Gulden
dc.contributor.authorKucukcoskun, Meric
dc.contributor.authorKiyan, Esen
dc.contributor.authorAdemoglu, Evin
dc.contributor.authorBaser, Ulku
dc.contributor.authorOztekin, Gorkem
dc.contributor.authorTanrikulu-Kucuk, Sevda
dc.contributor.authorOZKAN, Gulcihan
dc.contributor.authorYalcin, Funda
dc.date.accessioned2021-03-03T14:45:56Z
dc.date.available2021-03-03T14:45:56Z
dc.date.issued2014
dc.identifier.citationOztekin G., Baser U., Kucukcoskun M., Tanrikulu-Kucuk S., Ademoglu E., Isik G., OZKAN G., Yalcin F., Kiyan E., "The Association between Periodontal Disease and Chronic Obstructive Pulmonary Disease: A Case Control Study", COPD-JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE, cilt.11, sa.4, ss.424-430, 2014
dc.identifier.issn1541-2555
dc.identifier.othervv_1032021
dc.identifier.otherav_3b51b141-afac-4b70-9a93-339428e168c7
dc.identifier.urihttp://hdl.handle.net/20.500.12627/43846
dc.identifier.urihttps://doi.org/10.3109/15412555.2013.858316
dc.description.abstractIntroduction: Although there are studies evaluating the effects of periodontal health on chronic obstructive pulmonary disease (COPD), the effects of COPD - a systemic disease, on periodontal tissue is unknown. The aim of this study is to evaluate the effects of COPD on periodontal tissues by comparing COPD patients and controls. Methods: Fifty-two COPD patients and 38 non-COPD controls were included in this case-control study. Number of teeth, plaque index (PI), gingival index (GI), bleeding on probing, clinical attachment level and probing depth were included in the periodontal examination. In addition to clinical evaluations, gingival crevicular fluid (GCF) levels of high-sensitive C-reactive protein (hs-CRP), interleukin-1 beta (IL-1 beta) and prostaglandin-E-2 (PGE(2)), and serum hs-CRP levels were measured in COPD patients and the controls. Results: The number of teeth was significantly lower while PI and GI were significantly higher in COPD patients when compared to the controls. As well as serum hs-CRP levels, the GCF levels of hs-CRP, IL-1 beta and PGE(2) were significantly higher in COPD patients than the controls. Conclusion: Our results demonstrated that COPD may be associated with periodontal disease as manifested by lower number of teeth and higher levels of inflammatory mediators especially CRP in GCF. This finding may be a reflection of systemic effects of COPD on periodontal tissues. Poor oral health behavior of COPD patients have to be considered in larger size group studies in the future.
dc.language.isoeng
dc.subjectPulmonary and Respiratory Medicine
dc.subjectHealth Sciences
dc.subjectRespiratory Care
dc.subjectGöğüs Hastalıkları ve Allerji
dc.subjectDahili Tıp Bilimleri
dc.subjectSağlık Bilimleri
dc.subjectTıp
dc.subjectKlinik Tıp (MED)
dc.subjectKlinik Tıp
dc.subjectSOLUNUM SİSTEMİ
dc.titleThe Association between Periodontal Disease and Chronic Obstructive Pulmonary Disease: A Case Control Study
dc.typeMakale
dc.relation.journalCOPD-JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE
dc.contributor.departmentİstanbul Üniversitesi , ,
dc.identifier.volume11
dc.identifier.issue4
dc.identifier.startpage424
dc.identifier.endpage430
dc.contributor.firstauthorID21614


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