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Loss of heterozygosity at chromosome 14q is associated with poor prognosis in head and neck squamous cell carcinomas

dc.contributor.authorYamanaka, Noboru
dc.contributor.authorPalanduz, Sukru
dc.contributor.authorFukushima, Kunihiro
dc.contributor.authorShimizu, Kenji
dc.contributor.authorOzturk, Sukru
dc.contributor.authorPehlivan, Davut
dc.contributor.authorGunduz, Esra
dc.contributor.authorGunduz, Mehmet
dc.contributor.authorNagatsuka, Hitoshi
dc.contributor.authorBeder, Levent Bekir
dc.contributor.authorCengiz, Beyhan
dc.contributor.authorRivera, Rosario S.
dc.date.accessioned2021-03-03T15:49:13Z
dc.date.available2021-03-03T15:49:13Z
dc.date.issued2008
dc.identifier.citationPehlivan D., Gunduz E., Gunduz M., Nagatsuka H., Beder L. B. , Cengiz B., Rivera R. S. , Fukushima K., Palanduz S., Ozturk S., et al., "Loss of heterozygosity at chromosome 14q is associated with poor prognosis in head and neck squamous cell carcinomas", JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY, cilt.134, sa.12, ss.1267-1276, 2008
dc.identifier.issn0171-5216
dc.identifier.othervv_1032021
dc.identifier.otherav_40f88223-31c6-4e51-b56b-12f17319f48e
dc.identifier.urihttp://hdl.handle.net/20.500.12627/47406
dc.identifier.urihttps://doi.org/10.1007/s00432-008-0423-1
dc.description.abstractPurpose and methods Loss of heterozygosity (LOH) in a chromosomal location indicates the presence of an inactivated tumor suppressor gene (TSG). Inactivation of TSG has a functional role in the tumorigenesis of head and neck squamous cell carcinoma (HNSCC). Based on the recent evidences of a putative TSG on chromosome 14, we examined LOH on chromosome 14q using eight polymorphic microsatellite markers in 50 cases of HNSCCs.
dc.language.isoeng
dc.subjectSağlık Bilimleri
dc.subjectİç Hastalıkları
dc.subjectOnkoloji
dc.subjectDahili Tıp Bilimleri
dc.subjectTıp
dc.subjectKlinik Tıp (MED)
dc.subjectKlinik Tıp
dc.subjectONKOLOJİ
dc.titleLoss of heterozygosity at chromosome 14q is associated with poor prognosis in head and neck squamous cell carcinomas
dc.typeMakale
dc.relation.journalJOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
dc.contributor.departmentOkayama Eyalet Üniversitesi , ,
dc.identifier.volume134
dc.identifier.issue12
dc.identifier.startpage1267
dc.identifier.endpage1276
dc.contributor.firstauthorID12928


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