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Serum chymase levels in obese individuals: the relationship with inflammation and hypertension

dc.contributor.authorTopparmak, Erdal
dc.contributor.authorOner-Iyidogan, Yildiz
dc.contributor.authorTANRIKULU KÜÇÜK, SEVDA
dc.date.accessioned2021-03-02T18:19:23Z
dc.date.available2021-03-02T18:19:23Z
dc.date.issued2020
dc.identifier.citationTopparmak E., TANRIKULU KÜÇÜK S., Oner-Iyidogan Y., "Serum chymase levels in obese individuals: the relationship with inflammation and hypertension", TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI, cilt.45, ss.305-314, 2020
dc.identifier.issn0250-4685
dc.identifier.othervv_1032021
dc.identifier.otherav_8ed19021-06ed-4761-a98a-dd4cf3cd509a
dc.identifier.urihttp://hdl.handle.net/20.500.12627/4853
dc.identifier.urihttps://doi.org/10.1515/tjb-2018-0152
dc.description.abstractBackground: Inflammation related hypertension is reported in obesity due to synthesis of angiotensinII (Ang-II) and proinflammatory compounds in obese adipose tissue. Mast cell chymase (MC) also stimulate Ang-II synthesis, and activate transforming growth factor beta-1 (TGF-beta 1) and matrix metalloproteinase-9 (MMP-9). The aim of our study is to evaluate the relation of serum chymase levels, a serine protease enzyme secreted from mast cells, in obese patients with hypertension and cytokines that lead to cell damage.
dc.language.isoeng
dc.subjectBİYOKİMYA VE MOLEKÜLER BİYOLOJİ
dc.subjectMoleküler Biyoloji ve Genetik
dc.subjectYaşam Bilimleri (LIFE)
dc.subjectYaşam Bilimleri
dc.subjectMoleküler Biyoloji ve Genetik
dc.subjectSitogenetik
dc.subjectTemel Bilimler
dc.titleSerum chymase levels in obese individuals: the relationship with inflammation and hypertension
dc.typeMakale
dc.relation.journalTURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI
dc.contributor.departmentİstanbul Teknik Üniversitesi , ,
dc.identifier.volume45
dc.identifier.issue3
dc.identifier.startpage305
dc.identifier.endpage314
dc.contributor.firstauthorID2358056


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