dc.contributor.author | Colantonio, David | |
dc.contributor.author | Uras, Fikriye | |
dc.contributor.author | Ay, Pinar | |
dc.contributor.author | Uras, Ahmet Riza | |
dc.contributor.author | Adeli, Khosrow | |
dc.contributor.author | ÇAĞMAN, Zeynep | |
dc.contributor.author | Ozakpinar, Ozlem Bingol | |
dc.contributor.author | Cirakli, Zeynep | |
dc.contributor.author | GEDİKBAŞI, Asuman | |
dc.date.accessioned | 2021-03-03T16:36:41Z | |
dc.date.available | 2021-03-03T16:36:41Z | |
dc.date.issued | 2017 | |
dc.identifier.citation | ÇAĞMAN Z., Ozakpinar O. B. , Cirakli Z., GEDİKBAŞI A., Ay P., Colantonio D., Uras A. R. , Adeli K., Uras F., "Reference intervals for growth arrest-specific 6 protein in adults", SCANDINAVIAN JOURNAL OF CLINICAL & LABORATORY INVESTIGATION, cilt.77, sa.2, ss.109-114, 2017 | |
dc.identifier.issn | 0036-5513 | |
dc.identifier.other | av_45320326-be6c-4354-890a-a4fe94f21a7d | |
dc.identifier.other | vv_1032021 | |
dc.identifier.uri | http://hdl.handle.net/20.500.12627/50179 | |
dc.identifier.uri | https://doi.org/10.1080/00365513.2016.1275768 | |
dc.description.abstract | The objective of this study was to establish reference intervals for growth arrest-specific 6 (GAS6), a vitamin K-dependent protein, in human adult plasma according to the Guideline of Clinical and Laboratory Standards Institute (CLSI) C28-A3. Blood samples were collected from 308 healthy volunteers aged 18-72 (157 female, 151 male). A non-parametric approach was used to calculate the reference interval. The plasma GAS6 reference interval was determined, with 90% confidence interval: the lower limit (2.5 percentile) was 2.5 (1.9-3.1) g/L and the upper limit (97.5 percentile)=18.8 (18.0-22.3) g/L. Harris-Boyd's test did not suggest partitioning by age or gender: medians for males [7.8 (5.8-10.7) g/L] and females [9.9 (7.1-13.5) g/L]. Three age-subgroups were tested: 18-29 years (n=168); 30-44 years (n=73); 45-72 years (n=67). The intra- and inter-assay variations were 12.6% (mean, 5.2 +/- 0.7g/L) and 14.0% (mean, 9.2 +/- 1.3g/L), respectively. The mean recovery was 104%. This study reports plasma GAS6 reference intervals established first according to the guideline of CLSI C28-A3. | |
dc.language.iso | eng | |
dc.subject | Tıbbi Ekoloji ve Hidroklimatoloji | |
dc.subject | Dahili Tıp Bilimleri | |
dc.subject | Sağlık Bilimleri | |
dc.subject | Tıp | |
dc.subject | Klinik Tıp (MED) | |
dc.subject | Klinik Tıp | |
dc.subject | TIP, ARAŞTIRMA VE DENEYSEL | |
dc.title | Reference intervals for growth arrest-specific 6 protein in adults | |
dc.type | Makale | |
dc.relation.journal | SCANDINAVIAN JOURNAL OF CLINICAL & LABORATORY INVESTIGATION | |
dc.contributor.department | Marmara Üniversitesi , Eczacılık Fakültesi , Biyokimya Anabilim Dalı | |
dc.identifier.volume | 77 | |
dc.identifier.issue | 2 | |
dc.identifier.startpage | 109 | |
dc.identifier.endpage | 114 | |
dc.contributor.firstauthorID | 2214787 | |