Rapidly progressive subacute sclerosing panencephalitis presenting with acute loss of vision
Date
2011Author
Ekici, Baris
Aydinli, Nur
Caliskan, Mine
Ozmen, Meral
Tatli, Burak
Metadata
Show full item recordAbstract
A 10-year-old male presented with vision loss and behavioral changes. He had midpoint pupils with no reaction to light and normal funduscopic examination. Cranial magnetic resonance imaging revealed bilateral cortical lesions at parieto-occipital lobes. Elevated measles antibody titers in the cerebrospinal fluid confirmed the diagnosis of subacute sclerosing panencephalitis. Despite oral inosiplex and supportive care, patient developed generalized seizures with frequent myoclonic jerks and rapidly progressed into coma. Cortical blindness in subacute sclerosing panencephalitis can be an early indicator for fulminant course.
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