dc.contributor.author | Ekici, Barış | |
dc.contributor.author | Guler, Serhat | |
dc.contributor.author | ONAL, Hasan | |
dc.contributor.author | YEŞİL, GÖZDE | |
dc.contributor.author | Ozdil, Mine | |
dc.date.accessioned | 2021-03-03T16:46:16Z | |
dc.date.available | 2021-03-03T16:46:16Z | |
dc.date.issued | 2016 | |
dc.identifier.citation | Guler S., YEŞİL G., Ozdil M., Ekici B., ONAL H., "Sleep disturbances and serum vitamin D levels in children with autism spectrum disorder", INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE, cilt.9, sa.7, ss.14691-14697, 2016 | |
dc.identifier.issn | 1940-5901 | |
dc.identifier.other | vv_1032021 | |
dc.identifier.other | av_460c1b51-9718-43c5-aaa5-a4233a924cb5 | |
dc.identifier.uri | http://hdl.handle.net/20.500.12627/50716 | |
dc.description.abstract | Sleep problems are among the most prevalent comorbidities experienced by children with Autism Spectrum Disorder (ASD). There is a clinical and physiological basis for a link between 25(OH) D levels and sleep disorders. In this study we aimed to investigate the frequency of sleep disorders in ASD patients and its association with 25(OH) D levels, and whether or not these frequencies changed after 25(OH) D treatment. This prospective study included 60 consecutive patients diagnosed with ASD and matched healthy controls between the ages of 4 and 10. Patients then underwent 25(OH) D replacement therapy according to their deficiency levels. Pre- and post-therapy values were compared. Sleep disturbance was detected in 78.3% of ASD patients (n = 60) and 33.3% of the control group (n = 60). When we compared the pretreatment scores of sleep disturbance between ASD and control groups (n = 60), there were significant differences in bedtime resistance, sleep anxiety, parasomnias, daytime sleepiness, sleep duration, sleep-onset delay, night wakings subscales, and total scale score (p 0.05). In ASD patients, there was a significant negative correlation between serum 25(OH) D levels and the night wakings subscale (r = -0.301, p = 0.019). In control patients, there was a significant negative correlation between serum 25(OH) D levels and daytime sleepiness subscales (r = -0.269, p = 0.038). The results indicate that it may be suitable to use 25(OH) D replacement therapy in ASD patients and healthy individuals with sleep disturbances. | |
dc.language.iso | eng | |
dc.subject | Dahili Tıp Bilimleri | |
dc.subject | Tıbbi Ekoloji ve Hidroklimatoloji | |
dc.subject | TIP, ARAŞTIRMA VE DENEYSEL | |
dc.subject | Klinik Tıp | |
dc.subject | Klinik Tıp (MED) | |
dc.subject | Tıp | |
dc.subject | Sağlık Bilimleri | |
dc.title | Sleep disturbances and serum vitamin D levels in children with autism spectrum disorder | |
dc.type | Makale | |
dc.relation.journal | INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE | |
dc.contributor.department | Sağlık Bilimleri Üniversitesi , , | |
dc.identifier.volume | 9 | |
dc.identifier.issue | 7 | |
dc.identifier.startpage | 14691 | |
dc.identifier.endpage | 14697 | |
dc.contributor.firstauthorID | 104752 | |