dc.contributor.author | BUNDAK, R | |
dc.contributor.author | SAKA, N | |
dc.contributor.author | ANAK, S | |
dc.contributor.author | SUKUR, M | |
dc.contributor.author | GEDIKOGLU, G | |
dc.contributor.author | NEYZI, O | |
dc.date.accessioned | 2021-03-03T17:40:16Z | |
dc.date.available | 2021-03-03T17:40:16Z | |
dc.date.issued | 1995 | |
dc.identifier.citation | SAKA N., SUKUR M., BUNDAK R., ANAK S., NEYZI O., GEDIKOGLU G., "GROWTH AND PUBERTY IN THALASSEMIA MAJOR", JOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM, cilt.8, sa.3, ss.181-186, 1995 | |
dc.identifier.issn | 0334-018X | |
dc.identifier.other | av_4ad8995d-80b7-48e8-8a13-e5871411e1dd | |
dc.identifier.other | vv_1032021 | |
dc.identifier.uri | http://hdl.handle.net/20.500.12627/53760 | |
dc.identifier.uri | https://doi.org/10.1515/jpem.1995.8.3.181 | |
dc.description.abstract | Growth and sexual development were evaluated in 54 (29 female, 25 male) patients with beta-thalassemia major aged 2.7-21.3 years (mean 10.4 yr). Mean pretransfusion hemoglobin concentration was 7.8 +/- 0.7 mg/dl. All patients except 6 were on desferrioxamine. Age of starting of therapy was 6.8 +/- 3.9 years, Mean SDS values for height, weight and sitting height were significantly lower (p2 SD below the mean) was observed in 36 out of 54 patients. Among 11 patients over 14 years, 9 showed delay in onset or progression of puberty and 10 had growth retardation. Height SDS were negatively correlated with chronological age, age of onset of desferrioxamine and present serum ferritin levels (p<0.001). These findings indicate that abnormal growth and delayed puberty are frequent in transfusion dependent thalassemics. These can be partly overcome by early onset of chelating therapy. | |
dc.language.iso | eng | |
dc.subject | Klinik Tıp (MED) | |
dc.subject | Endokrinoloji ve Metabolizma Hastalıkları | |
dc.subject | İç Hastalıkları | |
dc.subject | Çocuk Sağlığı ve Hastalıkları | |
dc.subject | Dahili Tıp Bilimleri | |
dc.subject | Sağlık Bilimleri | |
dc.subject | Tıp | |
dc.subject | PEDİATRİ | |
dc.subject | ENDOKRİNOLOJİ VE METABOLİZMA | |
dc.subject | Klinik Tıp | |
dc.title | GROWTH AND PUBERTY IN THALASSEMIA MAJOR | |
dc.type | Makale | |
dc.relation.journal | JOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM | |
dc.contributor.department | , , | |
dc.identifier.volume | 8 | |
dc.identifier.issue | 3 | |
dc.identifier.startpage | 181 | |
dc.identifier.endpage | 186 | |
dc.contributor.firstauthorID | 116279 | |