Effect of paraoxonase 1 gene polymorphisms on clinical course of Henoch-Schonlein purpura
Tarih
2009Yazar
Ergen, Arzu
İsbir, TURGAY
Agachan, Bedia
Yilmaz, Alev
Yilmaz, HÜLYA
Sirin, Aydan
Emre, Sevinc
Bilge, Ilmay
Üst veri
Tüm öğe kaydını gösterÖzet
Background: Henoch-Schonlein purpura (HSP) is a systemic vasculitis; its pathogenesis is still unknown. Oxidative stress may play a role in the pathogenesis of HSP. Paraoxonase1 (PON1) is an antioxidant enzyme. Two polymorphisms have been defined in the coding region of the PON1 gene, Q/R192 and L/M55. In the present study, we aimed to investigate the effect of PON1 gene polymorphisms on the course and renal involvement of HSP in Turkish children.
Koleksiyonlar
- Makale [92796]