dc.contributor.author | Sabanci, P. A. | |
dc.contributor.author | Cakir, E. | |
dc.contributor.author | Imer, M. | |
dc.contributor.author | Ozbey, N. C. | |
dc.contributor.author | Bayindir, C. | |
dc.date.accessioned | 2021-03-03T17:59:37Z | |
dc.date.available | 2021-03-03T17:59:37Z | |
dc.date.issued | 2011 | |
dc.identifier.citation | Cakir E., Bayindir C., Sabanci P. A. , Imer M., Ozbey N. C. , "Pituitary macroadenoma with persisting dense lymphocytic infiltration in a young male patient", CLINICAL NEUROPATHOLOGY, cilt.30, sa.6, ss.318-323, 2011 | |
dc.identifier.issn | 0722-5091 | |
dc.identifier.other | av_4c9fd64a-77a9-4bcc-a266-242407a8fe8a | |
dc.identifier.other | vv_1032021 | |
dc.identifier.uri | http://hdl.handle.net/20.500.12627/54857 | |
dc.identifier.uri | https://doi.org/10.5414/np300378 | |
dc.description.abstract | Context: Lymphocytic anterior hypophysitis in association with a pituitary adenoma was reported previously. In rare instance, inflammatory infiltration was confined to adenoma tissue itself, excluding anterior pituitary. Case: The patient a 27-year-old male presented with visual field defect. Further examination revealed a pituitary mass with suprasellar extension. Hormonal evaluation indicated mild hyperprolactinemia (42 ng/ml, normal < 19). After transsphenoidal resection, a pituitary adenoma showing cytoplasmic immunoreactivity to prolactin was identified. Dense and diffuse lymphocytic infiltration was seen within the tumor. At 15th month, a second transsphenoidal operation was necessary because of rapid development of visual compromise and headache. Excised surgical specimen consistent with previously resected adenoma showed diffuse lymphocytic infiltration composed of B and T cells within the adenoma tissue again. Conclusion: Presence of dense, hypophysitis-like lymphocytic infiltration within pituitary adenoma tissue obtained by two consecutive operations may reflect an host-mediated immune reaction to tumor. This rare finding could be challenging in terms of differential diagnosis and follow-up course. | |
dc.language.iso | eng | |
dc.subject | Temel Tıp Bilimleri | |
dc.subject | Biyokimya | |
dc.subject | Dahili Tıp Bilimleri | |
dc.subject | Nöroloji | |
dc.subject | Cerrahi Tıp Bilimleri | |
dc.subject | Patoloji | |
dc.subject | Yaşam Bilimleri | |
dc.subject | Temel Bilimler | |
dc.subject | Tıp | |
dc.subject | Sağlık Bilimleri | |
dc.subject | Yaşam Bilimleri (LIFE) | |
dc.subject | Biyoloji ve Biyokimya | |
dc.subject | PATOLOJİ | |
dc.subject | Klinik Tıp (MED) | |
dc.subject | Klinik Tıp | |
dc.subject | KLİNİK NEUROLOJİ | |
dc.title | Pituitary macroadenoma with persisting dense lymphocytic infiltration in a young male patient | |
dc.type | Makale | |
dc.relation.journal | CLINICAL NEUROPATHOLOGY | |
dc.contributor.department | İstanbul Üniversitesi , , | |
dc.identifier.volume | 30 | |
dc.identifier.issue | 6 | |
dc.identifier.startpage | 318 | |
dc.identifier.endpage | 323 | |
dc.contributor.firstauthorID | 202198 | |