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Magnetic field responsive methylcellulose-polycaprolactone nanocomposite gels for targeted and controlled release of 5-fluorouracil

dc.contributor.authorAroguz, Ayse Z.
dc.contributor.authorNikjoo, Dariush
dc.date.accessioned2021-03-03T18:05:48Z
dc.date.available2021-03-03T18:05:48Z
dc.date.issued2016
dc.identifier.citationNikjoo D., Aroguz A. Z. , "Magnetic field responsive methylcellulose-polycaprolactone nanocomposite gels for targeted and controlled release of 5-fluorouracil", INTERNATIONAL JOURNAL OF POLYMERIC MATERIALS AND POLYMERIC BIOMATERIALS, cilt.65, sa.8, ss.421-432, 2016
dc.identifier.issn0091-4037
dc.identifier.otherav_4d31fe59-6bd0-459f-87cd-0cb303697a68
dc.identifier.othervv_1032021
dc.identifier.urihttp://hdl.handle.net/20.500.12627/55229
dc.identifier.urihttps://doi.org/10.1080/00914037.2015.1129954
dc.description.abstract5-Fluorouracil loaded magnetic field sensitive methylcellulose and polycaprolactone gels were prepared and characterized by FTIR, XRD, TGA, SEM, and VSM. Swelling analysis supplied important information on drug diffusion properties. The release profile of gels was investigated in different buffer solutions and the highest release values were observed at pH=7.2. Release kinetic was analyzed using an empirical equation to clarify the transport properties of drug. The effects of nanoparticle concentration and applying external magnetic field were investigated on release profile. The results indicated that the drug release decreased by both, applying external magnetic field and increasing the concentration of Fe3O4 nanoparticles.
dc.language.isoeng
dc.subjectTemel Bilimler
dc.subjectMühendislik ve Teknoloji
dc.subjectTemel Bilimler (SCI)
dc.subjectPolimer Karakterizasyonu
dc.subjectFizikokimya
dc.subjectKimya
dc.subjectPOLİMER BİLİMİ
dc.subjectMühendislik, Bilişim ve Teknoloji (ENG)
dc.subjectMalzeme Bilimi
dc.subjectMALZEME BİLİMİ, BİYOMATERYAL
dc.titleMagnetic field responsive methylcellulose-polycaprolactone nanocomposite gels for targeted and controlled release of 5-fluorouracil
dc.typeMakale
dc.relation.journalINTERNATIONAL JOURNAL OF POLYMERIC MATERIALS AND POLYMERIC BIOMATERIALS
dc.contributor.departmentİstanbul Üniversitesi , ,
dc.identifier.volume65
dc.identifier.issue8
dc.identifier.startpage421
dc.identifier.endpage432
dc.contributor.firstauthorID227465


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