BRAF, NRAS, KIT, TERT, GNAQ/GNA11 mutation profile analysis of head and neck mucosal melanomas: a study of 42 cases

Date
2017
Author
Yilmazbayhan, Dilek
Yilmaz, Ismail
Bilgic, Bilge
Taskin, Orhun Cig
Sari, Sule Ozturk
Buyukbabani, Nesimi
Comoglu, Senol
NARLI, Gizem
Sen, Fatma
Firat, Pinar
Ozluk, Yasemin
Metadata
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Abstract
Head and neck mucosal melanoma (HNMuM), which occurs mostly in the sinonasal and oral cavity, constitutes less than 1% of all malignant melanomas. Treatment options fail to improve the prognosis of this aggressive tumour that has low overall survival rates. Thus, development of new targeted therapies is essential. Unfortunately, limited data exist regarding their molecular profile.
URI
http://hdl.handle.net/20.500.12627/56293
https://doi.org/10.1016/j.pathol.2016.09.065
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