Basit öğe kaydını göster

dc.contributor.authorEskazan, Ahmet Emre
dc.date.accessioned2021-03-03T18:59:16Z
dc.date.available2021-03-03T18:59:16Z
dc.date.issued2016
dc.identifier.citationEskazan A. E. , "Bortezomib therapy in patients with relapsed/refractory acquired thrombotic thrombocytopenic purpura", ANNALS OF HEMATOLOGY, cilt.95, sa.11, ss.1751-1756, 2016
dc.identifier.issn0939-5555
dc.identifier.othervv_1032021
dc.identifier.otherav_52199046-eb6c-4c59-9e99-a5d5e1de6ddb
dc.identifier.urihttp://hdl.handle.net/20.500.12627/58317
dc.identifier.urihttps://doi.org/10.1007/s00277-016-2804-x
dc.description.abstractTherapeutic plasma exchange (TPE) has dramatically improved the prognosis of acquired thrombotic thrombocytopenic purpura (TTP), and TPE and corticosteroids are the mainstays of treatment of acquired TTP. However, a subset of patients may remain refractory to this treatment modality, or have an initial response but relapse after the discontinuation of TPE during the follow-up. While managing patients with relapsed/refractory acquired TTP, there are several therapeutic maneuvers, which can be considered. Recently, there came some papers regarding the use of bortezomib in relapsed or refractory acquired TTP, and in this review, this indication of bortezomib was evaluated along with the current data available. In seven published papers, 12 patients with relapsed/refractory acquired TTP received bortezomib, of which 11 survived the acute episodes and maintained remission. Bortezomib may serve as an adjunct treatment, but prospective trials are needed to determine the dosing, administration route, and the treatment schedule of this treatment option in patients with relapsed/refractory TTP.
dc.language.isoeng
dc.subjectHematoloji
dc.subjectSağlık Bilimleri
dc.subjectİç Hastalıkları
dc.subjectDahili Tıp Bilimleri
dc.subjectTıp
dc.subjectKlinik Tıp (MED)
dc.subjectKlinik Tıp
dc.subjectHEMATOLOJİ
dc.titleBortezomib therapy in patients with relapsed/refractory acquired thrombotic thrombocytopenic purpura
dc.typeMakale
dc.relation.journalANNALS OF HEMATOLOGY
dc.contributor.departmentİstanbul Üniversitesi , Açık ve Uzaktan Eğitim Fakültesi , Coğrafya
dc.identifier.volume95
dc.identifier.issue11
dc.identifier.startpage1751
dc.identifier.endpage1756
dc.contributor.firstauthorID236287


Bu öğenin dosyaları:

DosyalarBoyutBiçimGöster

Bu öğe ile ilişkili dosya yok.

Bu öğe aşağıdaki koleksiyon(lar)da görünmektedir.

Basit öğe kaydını göster