Effects of levetiracetam on blood-brain barrier disturbances following hyperthermia-induced seizures in rats with cortical dysplasia
Author
Kucuk, Mutlu
Kemikler, Gonul
Elmas, Imdat
Ahishali, Bulent
Arican, Nadir
Kalayci, Rivaze
Ekizoglu, Oğuzhan
Kaya, Mehmet
Gurses, Candan
Orhan, Nurcan
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Aims: The mechanisms underlying the changes in blood-brain barrier (BBB) integrity and the generation of seizures in childhood associated with preexisting brain lesions like cortical dysplasia (CD) are poorly understood. We investigated the effects of levetiracetam (LEV) on BBB integrity and the survival during hyperthermic seizures in rats with CD.
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