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dc.contributor.authorBITISIK, O
dc.contributor.authorYazici, Hülya
dc.contributor.authorDALAY, N
dc.contributor.authorSAYHAN, Nazife Şebnem
dc.contributor.authorBUDAK, M
dc.date.accessioned2021-03-03T19:07:48Z
dc.date.available2021-03-03T19:07:48Z
dc.identifier.citationSAYHAN N. Ş. , Yazici H., BUDAK M., BITISIK O., DALAY N., "P53 codon 72 genotypes in colon cancer. Association with human papillomavirus infection", RESEARCH COMMUNICATIONS IN MOLECULAR PATHOLOGY AND PHARMACOLOGY, cilt.109, ss.25-34, 2001
dc.identifier.issn1078-0297
dc.identifier.othervv_1032021
dc.identifier.otherav_52de3f08-c1fb-4dc4-943e-86b7c2796084
dc.identifier.urihttp://hdl.handle.net/20.500.12627/58790
dc.description.abstractIt has been reported that the p53Arg homozygous genotype could be a potential genetic risk factor for cancer. In this study are investigated the proportion of p53 codon 72 genotypes in patients with colon cancer and compared to a control population. A region of the p53 gene containing the polymorphic site was amplified by PCR and the genotypes were determined by restriction enzyme digestion. No significant difference was found between genotype frequencies in the study groups. Infection with human papilloma virus was also investigated in the tumor samples. HPV Is and HPV 33 infection was observed in a considerable number of the tumor samples. Incidence of HPV infection did not show a correlation with the genotypes. Thus the p53 genotypes do not seem to be associated with risk of colon cancer or HPV infection.
dc.language.isoeng
dc.subjectEczacılık
dc.subjectTemel Eczacılık Bilimleri
dc.subjectYaşam Bilimleri
dc.subjectMoleküler Biyoloji ve Genetik
dc.subjectSitogenetik
dc.subjectTemel Bilimler
dc.subjectFarmakoloji ve Toksikoloji
dc.subjectSağlık Bilimleri
dc.subjectFARMAKOLOJİ VE ECZACILIK
dc.subjectYaşam Bilimleri (LIFE)
dc.subjectMoleküler Biyoloji ve Genetik
dc.subjectBİYOKİMYA VE MOLEKÜLER BİYOLOJİ
dc.titleP53 codon 72 genotypes in colon cancer. Association with human papillomavirus infection
dc.typeMakale
dc.relation.journalRESEARCH COMMUNICATIONS IN MOLECULAR PATHOLOGY AND PHARMACOLOGY
dc.contributor.department, ,
dc.identifier.volume109
dc.identifier.startpage25
dc.identifier.endpage34
dc.contributor.firstauthorID57149


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