TREATMENT OF WILMS TUMOR: A Report from the Turkish Pediatric Oncology Group (TPOG)

Date
2010
Author
MELİKOĞLU, MUSTAFA
YALÇIN, BİLGEHAN
Hazar, Volkan
Yoruk, Asim
Tokuc, Guelnur
Akici, Ferhan
Buyukpamukcu, Nebil
Kale, Guelsev
Atahan, Lale
AKYÜZ, CANAN
Karpuzoglu, Guelten
Olgun, Nur
Ayan, Inci
OĞUZ, AYNUR
Yaris, Nilguen
Dagdemir, Ayhan
Sander, Serdar
Kuyumcuoglu, Ugur
Ozseker, Naciye
Corapcioglu, Funda
Tanyeli, Atilla
Duezovali, Oeznur
Aydin, G. Burca
Buyukpamukcu, Muenevver
Dervisoglu, Serguelen
Atkovar, Guelyuez Akyil
Buyukunal, Cenk
Darendeliler, Emin
Yildiz, Inci
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Abstract
Aim: To standardize diagnosis and treatment of childhood Wilms tumor (WT) in Turkey. Methods and patients: Between 1998 and 2006, WT patients were registered from 19 centers. Patients 2 years had significantly more advanced disease. 1/11 cases with recurrent disease died; 2/165 had progressive disease, 2/165 had secondary cancers, and all 4 died. In all cases 4-year OS and EFS were 92.8 and 86.5%, respectively. Both OS and EFS were significantly worse in stage IV. Conclusions: Despite problems in patient management and follow-up, treatment results were encouraging in this first national experience with a multicentric study in pediatric oncology. Revisions and modifications are planned to further improve results and minimize short- and long-term side effects.
URI
http://hdl.handle.net/20.500.12627/59387
https://doi.org/10.3109/08880010903447375
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