NEPHROTOXICITY OF GENTAMICIN AND COTRIMOXAZOLE COMBINATION IN RATS
Date
1994Author
UYSAL, V
STOHS, SJ
URAS, F
CEVIKBAS, U
YARDIMCI, T
IZZETTIN, FV
AYCA, B
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1. The nephrotoxicity of gentamicin is well known. However, little information is available regarding the combined effects of gentamicin plus co-trimoxazole (sulfamethoxazole-trimethoprim). Therefore, Wistar rats were treated daily with 100 mg/kg gentamicin or 100 mg/kg gentamicin plus 30 mg/kg trimethoprim-150 mg/kg sulfamethoxazole for 14 days.
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