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dc.contributor.authorTabak, F.
dc.contributor.authorSonneveld, M. J.
dc.contributor.authorde Knegt, R. J.
dc.contributor.authorBoonstra, A.
dc.contributor.authorHansen, B. E.
dc.contributor.authorJanssen, H. L. A.
dc.contributor.authorvan Campenhout, M. J. H.
dc.contributor.authorBrouwer, W. P.
dc.contributor.authorvan Oord, G. W.
dc.contributor.authorXie, Q.
dc.contributor.authorZhang, Q.
dc.contributor.authorZhang, N.
dc.contributor.authorGuo, S.
dc.contributor.authorStreinu-Cercel, A.
dc.contributor.authorWang, J.
dc.contributor.authorPas, S. D.
dc.date.accessioned2021-03-03T21:22:35Z
dc.date.available2021-03-03T21:22:35Z
dc.date.issued2016
dc.identifier.citationvan Campenhout M. J. H. , Brouwer W. P. , van Oord G. W. , Xie Q., Zhang Q., Zhang N., Guo S., Tabak F., Streinu-Cercel A., Wang J., et al., "Hepatitis B core-related antigen levels are associated with response to entecavir and peginterferon add-on therapy in hepatitis B e antigen-positive chronic hepatitis B patients", CLINICAL MICROBIOLOGY AND INFECTION, cilt.22, sa.6, 2016
dc.identifier.issn1198-743X
dc.identifier.othervv_1032021
dc.identifier.otherav_5ed06245-d813-466e-a91c-2ef4d91524f5
dc.identifier.urihttp://hdl.handle.net/20.500.12627/66269
dc.identifier.urihttps://doi.org/10.1016/j.cmi.2016.02.002
dc.description.abstractHepatitis B core-related antigen (HBcrAg), a new serum marker, may be useful in monitoring chronic hepatitis B infection. HBcrAg was measured in 175 hepatitis B e antigen-positive patients treated with entecavir (ETV) with or without peginterferon (PEG-IFN) add-on therapy. Decline in HBcrAg was stronger in patients with vs. without combined response (ETV: -3.22 vs. -1.71 log U/mL, p <0.001; PEG-IFN add-on: -3.16 vs. -1.83 IU/mL, p <0.001) and in patients with vs. without hepatitis B surface antigen (HBsAg) response (ETV: -2.60 vs. -1.74 log U/mL, p <0.001; PEG-IFN addon: -2.38 vs. -2.15 log U/mL, p = 0.31). HBcrAg was associated with combined response (adjusted odds ratio 0.3, 95% confidence interval 0.2-0.5, p <0.001), but was not superior to quantitative HBsAg (qHBsAg). (C) 2016 Published by Elsevier Ltd on behalf of European Society of Clinical Microbiology and Infectious Diseases.
dc.language.isoeng
dc.subjectTemel Bilimler
dc.subjectBULAŞICI HASTALIKLAR
dc.subjectİmmünoloji
dc.subjectYaşam Bilimleri (LIFE)
dc.subjectMikrobiyoloji
dc.subjectYaşam Bilimleri
dc.titleHepatitis B core-related antigen levels are associated with response to entecavir and peginterferon add-on therapy in hepatitis B e antigen-positive chronic hepatitis B patients
dc.typeMakale
dc.relation.journalCLINICAL MICROBIOLOGY AND INFECTION
dc.contributor.departmentErasmus University Rotterdam , ,
dc.identifier.volume22
dc.identifier.issue6
dc.contributor.firstauthorID233103


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