dc.contributor.author | Tabak, F. | |
dc.contributor.author | Sonneveld, M. J. | |
dc.contributor.author | de Knegt, R. J. | |
dc.contributor.author | Boonstra, A. | |
dc.contributor.author | Hansen, B. E. | |
dc.contributor.author | Janssen, H. L. A. | |
dc.contributor.author | van Campenhout, M. J. H. | |
dc.contributor.author | Brouwer, W. P. | |
dc.contributor.author | van Oord, G. W. | |
dc.contributor.author | Xie, Q. | |
dc.contributor.author | Zhang, Q. | |
dc.contributor.author | Zhang, N. | |
dc.contributor.author | Guo, S. | |
dc.contributor.author | Streinu-Cercel, A. | |
dc.contributor.author | Wang, J. | |
dc.contributor.author | Pas, S. D. | |
dc.date.accessioned | 2021-03-03T21:22:35Z | |
dc.date.available | 2021-03-03T21:22:35Z | |
dc.date.issued | 2016 | |
dc.identifier.citation | van Campenhout M. J. H. , Brouwer W. P. , van Oord G. W. , Xie Q., Zhang Q., Zhang N., Guo S., Tabak F., Streinu-Cercel A., Wang J., et al., "Hepatitis B core-related antigen levels are associated with response to entecavir and peginterferon add-on therapy in hepatitis B e antigen-positive chronic hepatitis B patients", CLINICAL MICROBIOLOGY AND INFECTION, cilt.22, sa.6, 2016 | |
dc.identifier.issn | 1198-743X | |
dc.identifier.other | vv_1032021 | |
dc.identifier.other | av_5ed06245-d813-466e-a91c-2ef4d91524f5 | |
dc.identifier.uri | http://hdl.handle.net/20.500.12627/66269 | |
dc.identifier.uri | https://doi.org/10.1016/j.cmi.2016.02.002 | |
dc.description.abstract | Hepatitis B core-related antigen (HBcrAg), a new serum marker, may be useful in monitoring chronic hepatitis B infection. HBcrAg was measured in 175 hepatitis B e antigen-positive patients treated with entecavir (ETV) with or without peginterferon (PEG-IFN) add-on therapy. Decline in HBcrAg was stronger in patients with vs. without combined response (ETV: -3.22 vs. -1.71 log U/mL, p <0.001; PEG-IFN add-on: -3.16 vs. -1.83 IU/mL, p <0.001) and in patients with vs. without hepatitis B surface antigen (HBsAg) response (ETV: -2.60 vs. -1.74 log U/mL, p <0.001; PEG-IFN addon: -2.38 vs. -2.15 log U/mL, p = 0.31). HBcrAg was associated with combined response (adjusted odds ratio 0.3, 95% confidence interval 0.2-0.5, p <0.001), but was not superior to quantitative HBsAg (qHBsAg). (C) 2016 Published by Elsevier Ltd on behalf of European Society of Clinical Microbiology and Infectious Diseases. | |
dc.language.iso | eng | |
dc.subject | Temel Bilimler | |
dc.subject | BULAŞICI HASTALIKLAR | |
dc.subject | İmmünoloji | |
dc.subject | Yaşam Bilimleri (LIFE) | |
dc.subject | Mikrobiyoloji | |
dc.subject | Yaşam Bilimleri | |
dc.title | Hepatitis B core-related antigen levels are associated with response to entecavir and peginterferon add-on therapy in hepatitis B e antigen-positive chronic hepatitis B patients | |
dc.type | Makale | |
dc.relation.journal | CLINICAL MICROBIOLOGY AND INFECTION | |
dc.contributor.department | Erasmus University Rotterdam , , | |
dc.identifier.volume | 22 | |
dc.identifier.issue | 6 | |
dc.contributor.firstauthorID | 233103 | |