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Synthesis, computational study, and evaluation of in vitro antimicrobial, antibiofilm, and anticancer activities of new sulfanyl aminonaphthoquinone derivatives

dc.contributor.authorKara, Emel Mataraci
dc.contributor.authorTuyun, Amaç Fatih
dc.contributor.authorBayrak, Nilufer
dc.contributor.authorYildirim, Hatice
dc.contributor.authorFujıta, Mikako
dc.contributor.authorCelik, Berna Ozbek
dc.contributor.authorNasırı, Hamid R.
dc.contributor.authorOtsuka, Masami
dc.contributor.authorCıftcı, Halil I.
dc.contributor.authorGupta, Girish Kumar
dc.date.accessioned2021-03-04T09:00:40Z
dc.date.available2021-03-04T09:00:40Z
dc.date.issued2017
dc.identifier.citationBayrak N., Yildirim H., Tuyun A. F. , Kara E. M. , Celik B. O. , Gupta G. K. , Cıftcı H. I. , Fujıta M., Otsuka M., Nasırı H. R. , "Synthesis, computational study, and evaluation of in vitro antimicrobial, antibiofilm, and anticancer activities of new sulfanyl aminonaphthoquinone derivatives", Letters in Drug Design and Discovery, cilt.14, sa.6, ss.647-661, 2017
dc.identifier.issn1570-1808
dc.identifier.othervv_1032021
dc.identifier.otherav_663bd5b8-25e8-4881-8a96-9309991b3304
dc.identifier.urihttp://hdl.handle.net/20.500.12627/71005
dc.identifier.urihttps://doi.org/10.2174/1570180813666161020164931
dc.description.abstractBackground: A set of novel sulfanyl aminonaphthoquinone derivatives (5a-j) were synthesized starting from 2,3-dichloro-1,4-naphthoquinone (1). The amine substituents were introduced via a nucleophilic substitution at reflux temperature. Subsequent reactions of 2-chloro-3-arylamino-1,4-naphthoquinones (3a-d) with different thiols (4a-c) led to the formation of the desired amino-and thio-substituted products (5a-j).
dc.language.isoeng
dc.subjectEczacılık
dc.subjectTemel Eczacılık Bilimleri
dc.subjectYaşam Bilimleri
dc.subjectBiyokimya
dc.subjectTemel Bilimler
dc.subjectMultidisciplinary
dc.subjectPharmacology
dc.subjectGeneral Pharmacology, Toxicology and Pharmaceutics
dc.subjectPharmacology, Toxicology and Pharmaceutics (miscellaneous)
dc.subjectChemistry (miscellaneous)
dc.subjectGeneral Chemistry
dc.subjectPharmacology (medical)
dc.subjectPharmacy
dc.subjectDrug Guides
dc.subjectPhysical Sciences
dc.subjectLife Sciences
dc.subjectHealth Sciences
dc.subjectTemel Bilimler (SCI)
dc.subjectYaşam Bilimleri (LIFE)
dc.subjectDoğa Bilimleri Genel
dc.subjectKimya
dc.subjectFarmakoloji ve Toksikoloji
dc.subjectÇOK DİSİPLİNLİ BİLİMLER
dc.subjectKİMYA, TIP
dc.subjectFARMAKOLOJİ VE ECZACILIK
dc.subjectSağlık Bilimleri
dc.subjectKlinik Tıp (MED)
dc.titleSynthesis, computational study, and evaluation of in vitro antimicrobial, antibiofilm, and anticancer activities of new sulfanyl aminonaphthoquinone derivatives
dc.typeMakale
dc.relation.journalLetters in Drug Design and Discovery
dc.contributor.departmentİstanbul Üniversitesi , ,
dc.identifier.volume14
dc.identifier.issue6
dc.identifier.startpage647
dc.identifier.endpage661
dc.contributor.firstauthorID2521701


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